Results 91 to 100 of about 11,207 (252)

Evolución de la necesidad y cobertura de los programas de tratamiento con sustitutivos opioides e intercambio de jeringas en las prisiones españolas, 1992-2009

Revista Española de Sanidad Penitenciaria
Introducción: España es de los pocos países que ha implementado generalizadamente tratamientos con sustitutivos opioides (TSO) y programas de intercambio de jeringas (PIJ) para los consumidores de drogas en prisión.
L. de la Fuente, M. J. Bravo, E. Jiménez-Mejías, L. Sordo, J. Pulido, G. Barrio   +5 more
doaj  

The evaluation of needle exchange programs. [PDF]

American Journal of Public Health, 1994
D Vlahov, R S Brookmeyer
openaire   +1 more source

Vascularized Liver‐on‐a‐Microsphere Reveals Alanine‐Glucose Metabolism‐Driven Regulation of Liver Function and Injury

Advanced Science, EarlyView.
A vascularized liver‐on‐a‐microsphere system is developed to recreate lobule‐like cellular organization and endothelial barrier function within compartmentalized hydrogel particles. The platform enhances hepatic performance and reveals alanine‐glucose cycle activation linked to improved detoxification capacity, offering a high‐throughput microscale ...
Jingyang Li, Zengnan Wu, Yingrui Zhang, Shulang Chen, Yongning Lin, Shiyu Chen, Tong Xu, Xianli Meng, Yi Zhang, Jin‐Ming Lin   +9 more
wiley   +1 more source

History of injection drug use in the month preceding incarceration in Iranian prisons

Scientific Reports
This study aimed to investigate the prevalence and pattern of injecting drug use (IDU) in Iranian incarcerated people one month before their imprisonment.
Mitra Darbandi, Willi McFarland, Soheil Mehmandoost, Fatemeh Tavakoli, Maliheh Sadat Bazrafshan, Naser Nasiri, Ali Akbar Haghdoost, Meraj Sharifi, Roya Safari Faramani, Hamid Sharifi   +9 more
doaj   +1 more source

A Machine Vision‐Guided Microphysiological Platform With Automated Microfluidics Enables Longitudinal Biomarker Monitoring and Emulation of Translationally Relevant Exposure Scenarios

Advanced Science, EarlyView.
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen, Yi Zhong, Laura Dangel, Sonia Youhanna, Reza Zandi Shafagh, Jinhye Ryu, Domnica‐Gabriela Gurau, Mathias Haag, Thomas E. Mürdter, Yingxin Liang, Iro Beligiani, Nicole Ziegler, Sabine Willems, Nayere Taebnia, Wouter van der Wijngaart, Volker M. Lauschke   +15 more
wiley   +1 more source

Federal funding for needle exchange programs.

Medical science monitor : international medical journal of experimental and clinical research, 2010
The HIV/AIDS pandemic has affected millions across the globe. The sharing of needles, for reasons of economy or social relations, has become the most common mode of HIV transmission among injection drug users. Needle exchange programs, which provide many services in addition to the exchange of clean needles for contaminated needles, have proven ...
Peter A, Clark, Matthew, Fadus
openaire   +1 more source

Palmitoylation of PSD‐95 Orchestrates Learning‐Dependent Metaplasticity in the Amygdala and Fear Memory

Advanced Science, EarlyView.
This study reveals that fear learning specifically triggers PICK1/DHHC2‐dependent palmitoylation of PSD‐95 in the lateral amygdala. Fear conditioning induces the dissociation of DHHC5 from PSD‐95 and the association of PSD‐95 with DHHC2. DHHC2‐mediated palmitoylation of PSD‐95 is required for synaptic transmission and underlies fear learning–induced ...
Zu‐Cheng Shen, Yu‐Xuan Weng, Zhi‐Xuan Xia, Yue‐Ling Zhao, Qian‐Qian Ding, Si‐Ying Wang, Ting Cao, Xuan‐Ying Chen, Wu‐Cheng Tao, Shen Lin, Zhou Chen, Yi‐Xiao Luo   +11 more
wiley   +1 more source

PRO: Needle Exchange Programs Should Be Instituted to Reduce Hepatitis C Virus Transmission. [PDF]

Clin Liver Dis (Hoboken), 2018
Cotter TG, Stier MW, Aronsohn A.
europepmc   +1 more source

ZER1 Restrains Pressure Overload‐Induced Cardiac Remodeling by Targeting DVL2 for Gly/N‐Degron‐Dependent Degradation

Advanced Science, EarlyView.
Pressure overload suppresses cardiomyocyte ZER1, weakening CRL2Zer1‐mediated DVL2 degradation and allowing DVL2 accumulation. Elevated DVL2 activates CaMKII‐HDAC4‐MEF2C signaling, drives fetal gene reactivation, and promotes pathological remodeling.
Mingchao Jiang, Zhehao Lin, Lu Chen, Ying Ni, Jun Zhou, Wenjuan Zhang, Huilin Wang, Peifeng Ying, Xiu Lu, Kai Wang, Qingran Kong, Naxin Xu, Dingsheng Zhao, Jianwei Li, Guohui Zhong, Xingchen Meng, Sarkawt Hamad, Junmeng Zheng, Yuan Fu, Rongjiang Qin, Xuran Chu, Shangxuan Li, Youyou Li, Yili Wu, Yi Wang, Weihong Song, Yingxian Li, Shukuan Ling   +27 more
wiley   +1 more source

CON: Needle Exchange Programs Should Not Be Instituted to Reduce Hepatitis C Virus Transmission. [PDF]

Clin Liver Dis (Hoboken), 2018
O'Riordan K, Khan M, Mazulis A.
europepmc   +1 more source