Results 81 to 90 of about 3,886,676 (155)

Acute mechanical stretch enhances β‐adrenergic–protein kinase A signalling and increases susceptibility to ventricular arrhythmias

The Journal of Physiology, EarlyView.
Abstract figure legend Mechanical stretch alters Cav3‐associated membrane organisation and enhances β‐adrenergic receptor (βAR)–protein kinase A (PKA)‐dependent Ca2+ instability. Schematic overview of the experimental strategy and proposed mechanism: rat hearts were studied by Langendorff optical mapping using a fluid‐filled left ventricular (LV ...
Houcheng Wang, En‐Chi Lai, Zhen Hua, Chenyu Liu, Ivan Sherstnev, Jiarong Fu, Fu Siong Ng, Julia Gorelik   +7 more
wiley   +1 more source

Myocardial stretch‐induced ROS production is enhanced prior to the development of heart failure under TAC‐induced pressure overload

The Journal of Physiology, EarlyView.
Abstract figure legend To elucidate the relationship between oxidative stress in heart failure induced by chronic mechanical overload and physiological NOX2‐derived stretch‐induced reactive oxygen species (ROS) that support myocardial contractility during acute stretch, we investigated the changes in stretch‐induced ROS following transverse aortic ...
Yumiko Chiba, Keiko Kaihara, Hiroki Tanaka, Naoki Nakagawa, Gentaro Iribe   +4 more
wiley   +1 more source

Two‐Stage Power Management for Triboelectric Nanogenerators: Toward Reliable and Efficient Self‐Powered Systems

Safety Science and Technology, Volume 1, Issue 4, December 2026.
This review systematically outlines two‐stage power management circuits for TENGs, integrating AC–DC and DC–DC conversion to overcome high impedance and unstable output. It highlights strategies for efficient energy extraction and stable power delivery, enabling the development of reliable self‐powered systems for safety monitoring and applications in ...
Jiaxin Hu, Zhiyong Zhang, Haiyang Shao, Tianyu Shi, Baoling Yuan, Ming‐Lai Fu   +5 more
wiley   +1 more source

Giant abdominal hematoma from injection into an insulin ball during dual antithrombotic and corticosteroid therapy

Journal of Diabetes Investigation, EarlyView.
Yasuhiro Tanji, Hiroshi Komamura, Takashi Mita, Shojiro Sawada   +3 more
wiley   +1 more source

Light‐Driven Hydrogen Production From Water by An Oxygen‐Sensitive [NiFe] Hydrogenase in a Cyanobacterial Whole‐Cell Biocatalyst

Chemistry–Methods, Volume 6, Issue 11, November 2026.
Formation of H2 and O2 directly from water by Synechocystis with photosystem II. Under anaerobic conditions, a fraction of the photosynthetically derived electrons can be directed toward H2 evolution. Pseudomonas serves as the primary O2 sink by consuming O2 through citrate supported respiration. This interaction maintains anaerobic conditions required
Kang Lyu, Samuel Grimm, Ron Stauder, Stephan Klähn, Andreas Schmid   +4 more
wiley   +1 more source

Endoplasmic Reticulum Autophagy Enhancement Alleviates Synaptic Plasticity Dysfunction and Ameliorates Cognitive Impairment in SAE Mice by Relieving STING‐Associated Inhibition of PKM2 Activity

CNS Neuroscience &Therapeutics, Volume 32, Issue 11, November 2026.
In sepsis‐associated encephalopathy (SAE), enhanced micro‐ER‐phagy mediated by Sec62 facilitates the delivery of STING to lysosomes for degradation in hippocampal neurons. This process relieves STING‐mediated inhibition of PKM2 activity, which further modulates cellular energy metabolism indicators including the ATP/ADP and NAD+/NADH ratios ...
Xiaofeng Guo, Daqing Yin, Zhonghua Zhang, Yuanyuan Zhao, Yali Zhang, Ying Jiang, Zhanying Zhao, Tongwen Sun, Feihu Zhou, Xijing Zhang   +9 more
wiley   +1 more source

Numerical simulation of opening process in a bileaflet mechanical heart valve under pulsatile flow condition

, 2008
[[abstract]]Background and aim of the study: Most previous computational fluid dynamics (CFD) studies of blood flow in mechanical heart valves (MHVs) have not efficiently addressed the important features of moving leaflet and blood-leaflet interaction ...
Shi, YB; Zhao, Y; Yeo, TJH; Hwang, NHC
core  

A Protocol for Lab‐Scale Production of 13C‐Labeled Yeast Extract as Internal Standard for Metabolomics and Quantification of Intracellular Metabolites

Current Protocols, Volume 6, Issue 11, November 2026.
Abstract Metabolomics enables the profiling of small‐molecule metabolites, thereby capturing the biochemical state of a living organism at a given moment and making it possible to monitor the organism's cellular responses to stimuli. This technique has become a powerful tool in pharmaceutical research, the food industry, and microbial research ...
Miriam Cammaert, Rosalie Wouters, Jitske van Ede, Erik de Hulster, Christiaan Mooiman, Patricia van Dam, Martin Pabst, Walter van Gulik, Pascale Daran‐Lapujade   +8 more
wiley   +1 more source

An Ascorbic‐Acid Containing Poly(Carbonate) Urethane With Antioxidant Bioactivity for Application in Heart Valve Scaffold Development

Journal of Biomedical Materials Research Part A, Volume 114, Issue 11, November 2026.
ABSTRACT Prosthetic heart valve development consists of several branching, innovative strategies to mediate the complex native environment that wears down valve durability. Anti‐calcification treatments are being applied to pericardial tissue, durable polymers are being developed that mitigate oxidative degradation and stress cracking, and heart valve ...
Drake D. Pedersen, Keishi Kohyama, Taro Fujii, Marianna Barbuto, Sangho Ye, Sujeong Park, Flaviana Falci, Jooyoun Park, Keun Seok Seo, William Long, Antonio D'Amore, Seungil Kim, William R. Wagner   +12 more
wiley   +1 more source

Necrotic adrenal myelolipoma in a geriatric dog

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract Adrenal myelolipomas are rare in dogs and usually incidental findings. They appear as hyperechoic, heterogeneous masses on ultrasound and fat‑dominant lesions on computed tomography (CT). An 11‑year‑old Spaniel cross presented with a 2‑day history of diarrhoea, vomiting and polyuria/polydipsia.
Heather Durkin, Sophie Aspinall
wiley   +1 more source