Fabrication of Patterned Composite Microneedles via Inkjet Printing for Enhanced Drug Delivery
A novel inkjet printing‐based microneedle platform enabling multi‐material fabrication for customizable and scalable transdermal drug delivery. Abstract Microneedle (MN) technology offers a minimally invasive, patient‐friendly alternative to conventional hypodermic injections for dermal drug delivery.
Sanghyeok Jang +2 more
wiley +1 more source
Carbon sink-source dynamics influence bud awakening under warming and defoliation. [PDF]
Fernández-de-Uña L.
europepmc +1 more source
An engineering strategy to fabricate highly vascularized volumetric tissues with capillary networks is developed. Endothelial cell‐covered spheroidal microtissues with high structural integrity are efficiently produced using bioprinting technology. These spheroidal microtissues are then assembled and cultured under perfusion conditions, resulting in ...
Hyeongkwon Oh +5 more
wiley +1 more source
Development and External Validation of a Nomogram for Predicting Pain Risk Post-Transperineal Prostate Biopsy Using Multi-Parameter Analysis. [PDF]
Xu Y, Li X, Zhang Y, Xue P.
europepmc +1 more source
Granular Hydrogels as Modular Biomaterials: From Structural Design to Biological Responses
Granular hydrogels are now emerging as promising biomaterials due to their inherent microporousity, injectability, and modularity. They have shown improvements in cell viability and migration, cellular/tissue infiltration, host tissue integration, mitigated foreign body response, and tissue regeneration.
Asmasadat Vaziri +6 more
wiley +1 more source
Lower-canopy marcescence facilitates light use efficiency of upper-canopy needles in <i>Cunninghamia lanceolata</i> in southeast China: implications for plant growth-survival trade-offs. [PDF]
Zhou L +5 more
europepmc +1 more source
This study develops cyclic peptidepolymer conjugate nanotubes with hydrophobic, drug‐rich cores to enhance drug loading and stability, and demonstrates their responsive disassembly, pharmacokinetics, and anti‐tumour efficacy in colorectal cancer models using the anticancer drug SN‐38.
Sophie K. Hill +4 more
wiley +1 more source
Prospective, non-randomised, open-label pilot trial assessing feasibility, safety and treatment success of acupuncture in children with functional constipation: ACU-PILOT study protocol. [PDF]
Bloem MN +7 more
europepmc +1 more source
Transforming Cancer Diagnosis and Therapy Through Fluorescent Hydrogels: A Review
This article reviews fluorescent hydrogel systems for cancer detection, monitoring, and therapy. Mimicking the tumor microenvironment, these hydrogels enable real‐time imaging and targeted drug delivery. The review discusses design strategies, labeling techniques, and applications, highlighting challenges and future opportunities in cancer diagnostics ...
Elahe Masaeli +2 more
wiley +1 more source

