Results 71 to 80 of about 459,482 (377)

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Kinetic Monte Carlo Simulations for Birefringence Relaxation of Photo-Switchable Molecules on a Surface

open access: yes, 2016
Recent experiments have demonstrated that in a dense monolayer of photo-switchable dye Methyl-Red molecules the relaxation of an initial birefringence follows a power-law decay, typical for glass-like dynamics.
Charbonneau, Patrick   +2 more
core   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Comparison of Fe, Zn, Mn, Cu, Cd and Pb concentration in spruce needles collected in the area of Gdansk and Gdynia in Northern Poland

open access: yesEnvironmental Protection and Natural Resources, 2018
The aim of the investigation was to assess the utility of spruce needles as a potential material to be used for monitoring the contamination level of the environment of Tricity agglomeration (represented by Gdansk and Gdynia).
Konieczyński Paweł   +2 more
doaj   +1 more source

Cloud chambers and crystal growth: Effects of electrically enhanced diffusion on dendrite formation from neutral molecules [PDF]

open access: yes, 1999
We present an extension of the solvability theory for free dendrite growth that includes the effects of electrically enhanced diffusion of neutral polar molecules.
Libbrecht, Kenneth G.   +1 more
core   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Optimal Needle Placement for Prostate Rotating-Shield Brachytherapy (RSBT) [PDF]

open access: yesarXiv, 2021
Purpose: To present an efficient NEEdle Position Optimization (NEEPO) algorithm for prostate rotating shield brachytherapy (RSBT). With RSBT, the increased flexibility beyond conventional high-dose-rate brachytherapy (HDR-BT) due to the partially shielded radiation source has been shown by Adams et al. in 2020 to enable improved urethra sparing (23.1%),
arxiv  

On the Absorption Properties of Metallic Needles [PDF]

open access: yes, 2020
Needle-like metallic particles have been suggested to explain a wide variety of astrophysical phenomena, ranging from the mid-infrared interstellar extinction to the thermalization of starlight to generate the cosmic microwave background. These suggestions rely on the amplitude and the wavelength dependence of the absorption cross sections of metallic ...
arxiv   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Learning to Localize, Grasp, and Hand Over Unmodified Surgical Needles [PDF]

open access: yesarXiv, 2021
Robotic Surgical Assistants (RSAs) are commonly used to perform minimally invasive surgeries by expert surgeons. However, long procedures filled with tedious and repetitive tasks such as suturing can lead to surgeon fatigue, motivating the automation of suturing.
arxiv  

Home - About - Disclaimer - Privacy