Results 31 to 40 of about 4,823,352 (315)

Identifying Hidden Needs, Creating Breakthrough Products

, 2010
Too many new products fail. New products which are hard to differentiate from existing products won't capture the customer's imagination. The failure is due to a poor understanding of customers' needs.
Goffin, Keith, Lemke, Fred, Fred Lemke, Ursula Koners, Keith Goffin, Koners, Ursula   +5 more
core   +1 more source

The Need to Tic

Movement Disorders Clinical Practice, 2020
[no abstract available]
Giulia Di Lazzaro, Francesca Magrinelli, Christos Ganos, Kailash P. Bhatia   +3 more
openaire   +4 more sources

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Dohsa‐hou intervention for reciprocal interpersonal interaction for a girl with Kabuki syndrome and autism spectrum disorder

Clinical Case Reports, 2021
Although available evidence for psychosocial treatment for patients with Kabuki syndrome is limited, Dohsa‐hou, a psychomotor therapy, could be a treatment option for autism spectrum disorder associated with the disorder.
Juri Kawano, Haruo Fujino
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Exploring indicators of natural recovery from alcohol and drug use problems: findings from the life in recovery survey in Flanders

Substance Abuse Treatment, Prevention, and Policy
Introduction Research has established natural recovery (NR) as an important pathway to substance use recovery. Studies investigating correlates of NR have mainly focused on demographic and substance use variables rather than life circumstances.
Florian De Meyer, Amine Zerrouk, Clara De Ruysscher, Wouter Vanderplasschen   +3 more
doaj   +1 more source

Chaining Differential Reinforcement of Compliance and Functional Communication Training to Treat Challenging Behavior Maintained by Negative Reinforcement

Behavioral Sciences
Differential reinforcement of compliance (DRC) and functional communication training (FCT) are two effective treatments for escape-maintained behavior. They each, however, have unique limitations.
Emily L. Ferris, Alexandra R. Howard, Eleni Baker, Daniel J. Hodge, Andrew R. Craig, Henry S. Roane, William E. Sullivan   +6 more
doaj   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Pathway insights: exploring profiles and processes of drop-in students in relation to completion rates in second chance education

Frontiers in Psychology
IntroductionObtaining an upper secondary degree is highly esteemed for its economic and societal value. For students dropping out of school who return to education to earning an upper secondary degree (cf.
Lana Van Den Berghe, Sarah S. W. De Pauw, Stijn Vandevelde   +2 more
doaj   +1 more source