Results 241 to 250 of about 8,522,636 (303)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
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Learning Disability Practice, 1998
This article introduces training-needs analysis (TNA) and places the process in the broad context of a training strategy. It aims to inform nurses on how the principles of TNA can be applied to their own practice.
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This article introduces training-needs analysis (TNA) and places the process in the broad context of a training strategy. It aims to inform nurses on how the principles of TNA can be applied to their own practice.
openaire +2 more sources
1983
Publisher Summary Economic psychology is simply the attempt to explore the interconnections between economics and psychology in a systematic way and come up with a coherent interdisciplinary account of the phenomena to be observed at their interface. As an integrated field of study, it does not really exist in the English-speaking world, but it does ...
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Publisher Summary Economic psychology is simply the attempt to explore the interconnections between economics and psychology in a systematic way and come up with a coherent interdisciplinary account of the phenomena to be observed at their interface. As an integrated field of study, it does not really exist in the English-speaking world, but it does ...
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CHI '10 Extended Abstracts on Human Factors in Computing Systems, 2010
Needs analysis is a prerequisite to effective design, but typically is difficult and time consuming. We applied and extended our methods and tools in a case study helping a mission control group for the International Space Station. This domain illustrates the challenges of information-system domains that lack rigid, immutable, physical constraints and ...
Dorrit Billman +3 more
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Needs analysis is a prerequisite to effective design, but typically is difficult and time consuming. We applied and extended our methods and tools in a case study helping a mission control group for the International Space Station. This domain illustrates the challenges of information-system domains that lack rigid, immutable, physical constraints and ...
Dorrit Billman +3 more
openaire +1 more source
ACADEMICIA: An International Multidisciplinary Research Journal, 2021
AbstractThe article covers the fact that spiritual needs are a factor determining the level of development of society, moral ideals, goals and interests. Also, the importance of the system of spiritual needs in the creation of the third Renaissance Foundation has been scientifically analyzed.
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AbstractThe article covers the fact that spiritual needs are a factor determining the level of development of society, moral ideals, goals and interests. Also, the importance of the system of spiritual needs in the creation of the third Renaissance Foundation has been scientifically analyzed.
openaire +1 more source