Results 31 to 40 of about 9,190 (201)

Update of the list of qualified presumption of safety (QPS) recommended microbiological agents intentionally added to food or feed as notified to EFSA 22: Suitability of taxonomic units notified to EFSA until March 2025

open access: yesEFSA Journal, Volume 23, Issue 7, July 2025.
Abstract The qualified presumption of safety (QPS) process was developed to assess the safety of microorganisms used in food and feed chains. During the period covered by this Statement, no new information warranted changes to the status of previously recommended QPS taxonomic units.
EFSA Panel on Biological Hazards (BIOHAZ)   +28 more
wiley   +1 more source

State of the Art and Consensus Statements by Healthcare Providers, Patients, and Caregivers on Continuous Glucose Monitoring in Liver Glycogen Storage Diseases

open access: yesJournal of Inherited Metabolic Disease, Volume 48, Issue 3, May 2025.
ABSTRACT Continuous glucose monitoring (CGM) is increasingly used although not officially registered for the management of people living with liver glycogen storage diseases (GSDs). The aims of this study were twofold: (a) to investigate the current experiences of healthcare providers (HCPs), patients, and caregivers using CGM to monitor glucose ...
Terry G. J. Derks   +116 more
wiley   +1 more source

Rethinking the Diagnosis and Management of Antibody‐Mediated Rejection in Multidisciplinary Transplant Meetings: A Global Survey and Banff Working Group Recommendations

open access: yesClinical Transplantation, Volume 39, Issue 5, May 2025.
ABSTRACT Introduction The diagnosis of antibody‐mediated rejection (AMR) requires input from several transplant professionals. Bringing clinical and laboratory experts together may help standardize care. Yet, little is known about current global practices of multidisciplinary meetings for AMR management.
Ruth Sapir‐Pichhadze   +24 more
wiley   +1 more source

Recombinant Klotho administration after myocardial infarction reduces ischaemic injury and arrhythmias by blocking intracellular calcium mishandling and CaMKII activation

open access: yesThe Journal of Pathology, Volume 265, Issue 3, Page 342-356, March 2025.
Abstract Ischaemic heart disease (IHD) remains a major cause of death and morbidity. Klotho is a well‐known anti‐ageing factor with relevant cardioprotective actions, at least when renal dysfunction is present, but its actions are much less known when renal function is preserved.
Sara Vázquez‐Sánchez   +15 more
wiley   +1 more source

Identification and study of new NF‐κB‐inducing kinase ligands derived from the imidazolone scaffold

open access: yesArchiv der Pharmazie, Volume 358, Issue 1, January 2025.
A new family of NF‐κB‐inducing kinase (NIK) ligands bearing an imidazolone moiety were synthesized. The best compound showed a dose‐dependent inhibition of p100 to p50 processing in cellular assays, a key step in nuclear factor κB (NF‐κB) activation. Based on computational techniques, a plausible binding mode is proposed.
Francisco Maqueda‐Zelaya   +8 more
wiley   +1 more source

Avaliação do perfil epidemiológico e das dificuldades encontradas pelos pacientes para o atendimento de primeira consulta no ambulatório de triagem da nefrologia da UNIFESP

open access: yesBrazilian Journal of Nephrology, 2012
INTRODUÇÃO: O objetivo deste estudo foi avaliar o perfil epidemiológico dos pacientes e das dificuldades dos pacientes encaminhados, pelas unidades básicas de saúde (UBS) ou outros hospitais, ao ambulatório de triagem da disciplina de Nefrologia do ...
Cícera Sebastiana da Silva Padovani   +2 more
doaj   +1 more source

Comparative Prognostic Value of Glomerular Filtration Rate, Serum Cystatin C, Beta‐2‐Microglobulin and Albuminuria for Death and Chronic Kidney Disease Progression

open access: yesJournal of Clinical Laboratory Analysis, Volume 39, Issue 2, January 2025.
Serum creatinine and albuminuria are the core of most CKD prediction and progression risk models. We have compared the prognostic powers of serum B2M levels with albuminuria, CysC levels, and the CKD‐EPI (CKD‐Epidemiology Collaboration) GFR equations for mortality and CKD progression.
Isis Cerezo   +8 more
wiley   +1 more source

Nefrologia: uma especialidade pouco atrativa para os medicos peruanos?

open access: yesBrazilian Journal of Nephrology, 2014
Embora a Comissão Nacional de Especialização Médica (CONAREME) tenha aumentado o número de vagas para Nefrologia no Peru, não houve um aumento proporcional do número de participantes para esta especialidade, o que é preocupante em um contexto no qual são
Percy Herrera-Anazco   +2 more
doaj   +1 more source

Association of Total Mortality and Cardiovascular Endpoints With the Timing of the First and Second Systolic Peak of the Aortic Pulse Wave

open access: yesThe Journal of Clinical Hypertension, Volume 27, Issue 1, January 2025.
ABSTRACT Prognostic significance of the timing in the cardiac cycle of the first (TP1) and second (TP2) systolic peak of the central aortic pulse wave is ill‐defined. Incidence rates and standardized multivariable‐adjusted hazard ratios (HRs) of adverse health outcomes associated with TP1 and TP2, estimated by the SphygmoCor software, were assessed in ...
Yi‐Bang Cheng   +22 more
wiley   +1 more source

Depressed cardiac autonomic modulation in patients with chronic kidney disease

open access: yesBrazilian Journal of Nephrology, 2014
Introduction: A dysfunctional autonomic nervous system (ANS) has also been recognized as an important mechanism contributing to the poor outcome in CKD patients, with several studies reporting a reduction in heart rate variability (HRV).
Carlos Alberto de Oliveira   +8 more
doaj   +1 more source
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