Results 231 to 240 of about 246,906 (293)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Towards a holistic framework for multimodal LLM in 3D brain CT radiology report generation. [PDF]

Nat Commun
Li CY, Chang KJ, Yang CF, Wu HY, Chen W, Bansal H, Chen L, Yang YP, Chen YC, Chen SP, Chen SJ, Lirng JF, Chang KW, Chiou SH.   +13 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Evaluation of a text-mining application for the rapid analysis of free-text wildlife necropsy reports. [PDF]

PLoS One
Saverimuttu S, McInnes K, Warren K, Yeap L, Hunter S, Gartrell B, Pas A, Chatterton J, Jackson B.   +8 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Soft locality restrictions in negative concord: Evidence from the French future polarity effect. [PDF]

Nat Lang Linguist Theory
Liang Y, Amsili P, Burnett H.
europepmc   +1 more source

Testing semantic compositionality in baboons (Papio papio) through relearning and generalization. [PDF]

PLoS One
Reboul A, Claidière N, Dautriche I, Fagot J.   +3 more
europepmc   +1 more source

Hybrid natural language processing tool for semantic annotation of medical texts in Spanish. [PDF]

BMC Bioinformatics
Campillos-Llanos L, Valverde-Mateos A, Capllonch-Carrión A.   +2 more
europepmc   +1 more source

A Criterion for Categories on Which Every Grothendieck Topology is Rigid. [PDF]

Appl Categ Struct
Marquès J.
europepmc   +1 more source

Looks at what isn't there: eye movements on a blank screen when processing negation in a first and a second language. [PDF]

Front Hum Neurosci
Vanek N, Matić Škorić A, Košutar S, Matějka Š, Stone K.   +4 more
europepmc   +1 more source