Results 31 to 40 of about 62,891 (296)

Open Versus Closed Negative Pressure Wound Therapy For Contaminated and Dirty Surgical Wounds: A Quasi-Experimental Study

Pakistan Armed Forces Medical Journal
Objectives: To determine the efficacy of open versus closed negative pressure wound therapy for contaminated and dirty surgical wounds in terms of time duration to full wound healing. Study Design: Quasi-experimental study.
Saqib Hameed, Mubashir Hanif, Zaki Hussain Salamat, Sohail Ilyas, Omar Farooq, Shafqat Rehman   +5 more
doaj   +1 more source

Feasibility of a disposable canister-free negative-pressure wound therapy (NPWT) device for treating open wounds in horses

BMC Veterinary Research, 2019
Background Wounds are among the most common medical conditions affecting horses and have a major economic impact on the horse industry. Wound healing in horses is distinct to that documented in other species, and often results in delayed healing and ...
Louis Kamus, Marie Rameau, Christine Theoret   +2 more
doaj   +1 more source

Variations of negative pressure wound therapy

Journal of Surgical Technique and Case Report, 2011
No Abstract.
openaire   +4 more sources

Application of Negative Pressure Wound Therapy

Journal of Orthopaedic Trauma, 2021
Summary: The video depicts the materials and steps for applying negative pressure wound therapy. The clinical case involves a patient who had sustained a thigh Morel-Lavallee lesion that developed overlying skin necrosis and drainage that was treated with surgical debridement and the application of negative pressure wound therapy.
Lauren M, Tatman, Vamshi, Gajari, William T, Obremskey   +2 more
openaire   +3 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Combined negative pressure wound therapy with irrigation and dwell time and artificial dermis prevents infection and promotes granulation formation in a ruptured giant omphalocele: a case report

BMC Pediatrics, 2022
Background Omphalocele is a congenital abdominal wall defect of the umbilical cord insertion site. A giant omphalocele, with a fascial defect > 5 cm in diameter and/or containing > 50% of the liver within the hernia sac, can be challenging for pediatric ...
Yoichi Nakagawa, Hiroo Uchida, Akinari Hinoki, Chiyoe Shirota, Wataru Sumida, Satoshi Makita, Hizuru Amano, Masamune Okamoto, Aitaro Takimoto, Seiya Ogata, Shunya Takada, Daiki Kato, Yousuke Gohda   +12 more
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Negative-pressure wound therapy for deep groin vascular infections [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2016
Introduction. Infection of synthetic graft in the groin is a rare but devastating complication. When it occurs, several possibilities of treatment are available.
Matić Predrag, Tanasković Slobodan, Živić Rastko, Jocić Dario, Gajin Predrag, Babić Srđan, Soldatović Ivan, Vučurević Goran, Nenezić Dragoslav, Radak Đorđe   +9 more
doaj   +1 more source

Advances in the treatment of combat trauma to the extremities: photodynamic therapy and methods of plastic wound closure

Український журнал клінічної хірургії, 2023
Objective. To evaluate our own ten–year experience in the use of photodynamic therapy and plastic wound closure methods in the treatment of combat trauma victims using various photosensitizers and light sources, as well as tissue therapy.
Yu.V. Ivanova, S. M. Gramatyuk, I. A. Kryvoruchko, V. O. Prasol, K. V. Myasoedov   +4 more
doaj   +1 more source