In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Licosin, a multifunctional defensin peptide originated from the clinical fungus <i>Lichtheimia corymbifera</i> with antibacterial and potassium ion channel blocking effects. [PDF]
Chen W, Yu Y, Wu Y, Chen X, Shen B.
europepmc +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
"In order to increase net currents of the negative pionlike pi^- or muonlike mu^- particle under the method due to an electron and positive ion bunch, positive ions from the outside plasma must be supplied along the orbit of pi^- or mu^- particle within ...
"Uramoto, J."
core
Accuracy and Agreement of a 45 mg Versus a 75 mg <sup>13</sup>C-Urea Breath Test for the Diagnosis of <i>Helicobacter pylori</i> Infection in Adults: A Randomized Crossover Trial. [PDF]
Huang J, Xie Y, Huang J, Lu B, Chen Y.
europepmc +1 more source
How phagocytic cells kill bacteria: Lessons from a professional killer
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
iDualG4: A Dual-Channel Deep Learning Framework for Predicting In Vivo G-Quadruplexes. [PDF]
Li H, Dong L, Jia Y, Zheng C, Wei P.
europepmc +1 more source
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Ligation-Driven Electrochemical Magneto-Genoassay Platform Based on PNA Probes for the Multiple Detection of Soy and Mustard DNA in Wheat Flour. [PDF]
Fortunati S +11 more
europepmc +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source

