Results 131 to 140 of about 2,547,134 (311)

Social Distance and Affection: A Negative, Negative Correlation

The Psychological Record
Abstract Altruistic behavior is a function of social distance, but why do individuals put others at a particular distance? Social distance is a multidimensional concept, and affection is one of its dimensions. This study evaluated whether there is a negative correlation between social distance and an affection rating.
Alvaro Arturo Clavijo-Alvarez, Klaus Krejci-Muñoz, Juan Pablo Molano-Gallardo, Sulibeth Cruz-Chaparro   +3 more
openaire   +1 more source

The role of mental toughness and affect in academic success within a higher education setting

‘Mental Toughness’ is recognised as an important component in academic success (Robinson 2013) represented by the psychological qualities that determine how challenges are effectively addressed in pressurised situations (Dewhurst et al. 2012).
Fern Pollak, Liory, Cachia, Moira, Usher, Lee, Hunt, Frances, Lynam, Siobhan, Stock, Rosemary   +5 more
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Negative affect-induced food intake in non-dieting women is reward driven and associated with restrained-disinhibited eating subtype

, 2011
In humans the presence of negative affect is thought to promote food intake, but there is widespread variability. Susceptibility to negative affect-induced eating may depend on trait eating behaviours, notably ‘emotional eating’, ‘restrained eating’ and
Fay, Stephanie H., Graham Finlayson, Finlayson, Graham, Stephanie H. Fay   +3 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

The power of positivity: Exploring affective and social processes of change throughout a positive valence treatment for anxiety or depression

Journal of Mood and Anxiety Disorders
Objective: Social disconnection is common and disabling in persons with anxiety or depression, yet remains underexplored in treatment research. Proposed mechanisms underlying social disconnection include heightened negative valence system activation ...
Madeleine Rassaby, Samantha N. Adams, Murray B. Stein, Charles T. Taylor   +3 more
doaj   +1 more source

Giving or Taking: The Role of Dispositional Power Motivation and Positive Affect in Profit Maximization? [PDF]

Socio-economic decisions are commonly explained by rational cost vs. benefit considerations, whereas person variables have not usually been considered.
Martin Beckenkamp, Markus Quirin, Julius Kuhl   +2 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Predictor factors for teacher innovative behavior during curriculum reform: The role of cognitive flexibility, positive affect, and negative affect

REID (Research and Evaluation in Education)
Teacher innovative behavior is a key capability for maximizing teacher performance as well as the student learning process, especially when teachers face new changes in their education system such as curriculum reform. However, insufficient attention has
Khairunnisa Syafira Dumbi, Stephanie Yuanita Indrasari   +1 more
doaj   +1 more source