Results 171 to 180 of about 2,547,134 (311)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Negative Affect and Impulsivity in Adolescents with Non-Suicidal Self-Injury: The Moderating and Mediating Roles of Perceived Social Support

open access: yes
Bing Pan,1 Yun Gong,2 Meiyi Guo,3 Xiaohua Wang,1 Haitao Lu,1 Zheng Lin,1 Bingren Zhang3 1Department of Psychiatry, Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310009, People’s Republic of China ...
Guo M   +6 more
core  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Role of affect in construal of life stressors

open access: yes, 2013
The aim of the current study was to examine how construal of negative and positive life events and positive and negative affect are related. 240 participants were randomly distributed into a 2x2 between participants design [(Valence of scenario: Negative
Singh, Smita   +3 more
core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Insomnia in stimulant use disorders: Prevalence and associations with negative affect. [PDF]

open access: yesSleep Med
Bourtin IG   +5 more
europepmc   +1 more source

WHEN DOES NEGATIVE BRAND PUBLICITY HURT? The Moderating Influence of Analytic Versus Holistic Thinking [PDF]

open access: yes
Negative publicity can diminish positive consumer perceptions of a brand. We explore the impact of processing style on mitigating the effects of negative publicity.
Alokparna (Sonia) Basu Monga   +1 more
core  

Home - About - Disclaimer - Privacy