Results 81 to 90 of about 14,118,684 (408)

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

The Lighter Side of Pain: Do Positive Affective States Predict Memory of Pain Induced by Running a Marathon?

Journal of Pain Research, 2022
Luis Anunciação,1 Anna Carolina Portugal,2 J Landeira-Fernandez,1 Elżbieta A Bajcar,3 Przemysław Bąbel3 1Pontifical Catholic University of Rio de Janeiro – Brazil, Rio de Janeiro, 22451-900, Brazil; 2Federal University of Rio de ...
Anunciação L, Portugal AC, Landeira-Fernandez J, Bajcar EA, Bąbel P   +4 more
doaj  

Modelling the influence of personality and culture on affect and enjoyment in multimedia [PDF]

, 2015
Affect is evoked through an intricate relationship between the characteristics of stimuli, individuals, and systems of perception. While affect is widely researched, few studies consider the combination of multimedia system characteristics and human ...
Chandra, S, Ghinea, G, Lin, W, Scott, M
core   +2 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Symptom Similarities and Differences in Anxiety and Depressive Disorders [PDF]

Psikiyatride Güncel Yaklaşımlar, 2010
The question if there is a valid distinction between depression and anxiety disorders remains controversial. These two disorders have various overlaps in the symptomatology and sometimes it is difficult to make a clear diagnosis. The difficulty in making
Dilek Sirvanli Ozen, Elif Temizsu
doaj  

Passion, craving, and affect in online gaming: Predicting how gamers feel when playing and when prevented from playing [PDF]

, 2011
According to the Dualistic Model of Passion, two forms of passion can motivate a behavior: harmonious passion and obsessive passion. Across various life activities, studies have found that the two forms of passion show different relationships with affect,
Bartle, Carbonneau, Carbonneau, Ducheneaut, Gosling, Hays, Joachim Stoeber, Joshua A. Ward, Julian H. Childs, Lafrenière, Mageau, Mageau, Matt Harvey, Meng, Philippe, Przybylski, Ratelle, Rip, Rousseau, Smyth, Stoeber, Tabachnick, Taris, Vallerand, Vallerand, Vallerand, Vallerand, Wang, Wang, Watson, Young   +30 more
core   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Valence-specific EEG microstate modulations during self-generated affective states

Frontiers in Psychology
IntroductionThis study aims to explore the temporal dynamics of brain networks involved in self-generated affective states, specifically focusing on modulating these states in both positive and negative valences.
Karina Nazare, Karina Nazare, Miralena I. Tomescu, Miralena I. Tomescu   +3 more
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Temporal dynamics of positive and negative affect in adolescents: Associations with depressive disorders and risk

Journal of Mood and Anxiety Disorders
Alterations in dynamic affective processes are associated with dysregulated affect and depression. Although depression is often associated with heightened inertia (i.e., greater moment-to-moment correlation) and variability (i.e., larger departures from ...
George Abitante, David A. Cole, Christian Bean, Madison Politte-Corn, Qimin Liu, Anh Dao, Lindsay Dickey, Samantha Pegg, Autumn Kujawa   +8 more
doaj   +1 more source