Results 81 to 90 of about 2,556,506 (311)

Spontaneous Ultrasonic Vocalization Transmission in Adult, Male Long–Evans Rats Is Age-Dependent and Sensitive to EtOH Modulation

open access: yesBrain Sciences, 2020
Ultrasonic vocalizations (USVs) are well-established markers of motivational and emotional status. Recent work from our lab has provided novel evidence for a role of USVs in models of ethanol (EtOH) use.
Nitish Mittal   +3 more
doaj   +1 more source

A short empirical note on perfectionism and flourishing [PDF]

open access: yes, 2016
Flourishing describes an optimal state of mental health characterized by emotional, psychological, and social well-being. In a recent publication, Flett and Hewitt (2015) suggested that perfectionism prevents people from flourishing.
Stoeber, Joachim   +3 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

‘Man You’ve Been a Naughty Boy, You Let your Face Grow long’ On the celebration of negative affect in adolescence [PDF]

open access: yes, 2013
In this paper the authors explore the phenomena of positive attitudes towards negative affect among young adolescent as reflected in the appearance and behaviours of ‘radical peer crowds’, such as Punks, Goths and Emos.
Michalis Kakos (7598468)   +5 more
core  

Amygdala and ventromedial prefrontal cortex are inversely coupled during regulation of negative affect and predict the diurnal pattern of cortisol secretion among older adults [PDF]

open access: yes, 2006
Among younger adults, the ability to willfully regulate negative affect, enabling effective responses to stressful experiences, engages regions of prefrontal cortex (PFC) and the amygdala.
Thurow, Marchell E.   +10 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Affect intensity contributes to perfectionistic self-presentation in adolescents beyond perfectionism [PDF]

open access: yes, 2014
Perfectionistic self-presentation in adolescents is associated with psychological maladjustment and distress. Yet, no study so far has investigated what personality characteristics contribute to perfectionistic self-presentation in adolescence.
Stoeber, Joachim   +3 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Reducing negative affect with anodal transcranial direct current stimulation increases memory performance in young - but not in elderly - individuals [PDF]

open access: yes, 2018
Affect can have a direct impact on memory processing, which offers the opportunity to shape memory performance by modulating affective responses. The left dorsolateral prefrontal cortex (dlPFC) is functionally involved in both affect and memory, with an ...
Peter, Jessica
core  

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