Results 161 to 170 of about 4,503,165 (306)

Transcriptomic Profiling in Skeletal Muscle Identifies Associations With Knee Osteoarthritis: The Study of Muscle, Mobility and Aging

open access: yesArthritis &Rheumatology, EarlyView.
Objective The association between skeletal muscle gene expression and knee osteoarthritis (OA) was examined among older adult participants of the Study of Muscle, Mobility and Aging (SOMMA). Methods Inclusion criteria included knee radiographs and bulk RNA sequencing in vastus lateralis muscle, resulting in 523 participants (56% female).
Daniel S. Evans   +7 more
wiley   +1 more source

The Chernoff Modification of the Fisher Exact Test for the Difference of Two Binomial Probabilities [PDF]

open access: yes
To test the difference of two binomial probabilities, we will apply the Fisher exact test modified by Chernoff (2002), which will be called CMF test. The key idea is to use the P-value of Fisher exact test as a test statistic and this makes it possible ...
Takahashi, Hajime, Uematsu, Kazuki
core  

Plasma Proteomics Identifies Molecular Signatures and Biomarkers Associated With High Structural Damage in Ankylosing Spondylitis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Pathologic bone formation in ankylosing spondylitis (AS) is not fully reflected by systemic inflammation, limiting the utility of markers of inflammation for structural damage assessment. This study aimed to identify plasma protein signatures associated with structural damage severity in AS.
Tiantian Sun   +9 more
wiley   +1 more source

Geographically weighted negative binomial regression for spatial count data: Methodology and application. [PDF]

open access: yesMethodsX
Saifudin T   +6 more
europepmc   +1 more source

Electroconvulsive Therapy for Catatonia in Autistic and Non‐Autistic Patients: An Observational Study on Course, Efficacy, Aggression, and Self‐Injury Outcomes

open access: yesAutism Research, EarlyView.
ABSTRACT Catatonia occurs disproportionately in autistic individuals and may respond to electroconvulsive therapy (ECT), yet prior reports suggest greater treatment burden in this population. We compared longitudinal ECT utilization, safety, and clinical outcomes between autistic and non‐autistic patients with catatonia.
Joshua Ryan Smith   +15 more
wiley   +1 more source

On Ling's binomial and negative binomial distributions of order k

open access: yes
Type II binomial distribution of order k was introduced by Ling (1988). In this article the probability function, the probability generating function and asymptotic properties of the distribution are discussed.
Kashiwagi, N.   +3 more
core  

Practice‐level variation in potentially inappropriate prescribing in middle‐aged adults: A repeated cross‐sectional study in South London general practice

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim To quantify between‐practice variation in potentially inappropriate prescribing (PIP) among middle‐aged adults (45–64 years) in UK general practice, and to identify patient‐ and practice‐level characteristics associated with PIP. Methods Repeated cross‐sectional study using linked data from the Lambeth DataNet and Quality Outcomes Framework across ...
Ryan Jayesinghe   +6 more
wiley   +1 more source

Inappropriate prescribing of gastric acid suppressants: A systematic literature review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Inappropriate prescribing of gastric acid suppressants (GASs) may compromise treatment outcomes. This study aimed to examine the prevalence of inappropriate prescribing of GASs in all healthcare settings. Methods This PROSPERO‐registered systematic literature review used PubMed and Embase databases to identify original English‐language studies ...
Dhani Wijaya   +5 more
wiley   +1 more source

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