Results 221 to 230 of about 4,503,165 (306)

The life and work of Ernest Sydney Keeping

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract This article reviews the life and contributions of Ernest S. Keeping (1895–1984), a British‐born physicist who became a mathematics professor at the University of Alberta in 1929. He played a pivotal role in shaping the university's Mathematics Department, serving as its head from 1954 to 1961, and continuing to teach until 1970, nine years ...
David R. Bellhouse, Christian Genest
wiley   +1 more source

Negative Binomial Regression

open access: yesJournal of the Royal Statistical Society Series A: Statistics in Society, 2008
openaire   +1 more source

Learning sparse mixture‐of‐experts generalized linear models in ultrahigh dimensions

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract Motivated by the challenges of heterogeneity and high dimensionality in the analysis of modern data, we investigate continuous regularization methods for learning sparse mixture‐of‐experts generalized linear models (MoE‐GLM). Although there are foundational results about regularized estimators in a broad class of regression models including ...
Pengqi Liu, Abbas Khalili
wiley   +1 more source

extBatchMarking: An R package for hidden Markov models for extended batch data

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract We describe a new R package for extended batch‐mark methods. Extended batch marking is a valuable and efficient technique for estimating population sizes and survival probabilities of wild animals. It assigns the same identifier to a group of animals simultaneously, allowing researchers to track their survival over time.
Kehinde Olobatuyi   +4 more
wiley   +1 more source

Population Pharmacokinetics and Exposure‐Response Analyses to Support Cofetuzumab Pelidotin (ABBV‐647) Dose Optimization in Non‐Small Cell Lung Cancer Patients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Cofetuzumab pelidotin (Cofe‐P) is an anti‐protein tyrosine kinase 7 (PTK7) antibody‐drug conjugate (ADC) being investigated for the treatment of adults with PTK7‐expressing, recurrent non‐small cell lung cancer (NSCLC). The first‐in‐human (FIH) trial demonstrated tolerability of dosages ≤ 2.8 mg/kg once every 3 weeks (Q3W) and ≤ 3.2 mg/kg Q2W ...
Carla Biesdorf   +8 more
wiley   +1 more source

Enhancing Evidence Generation by Linking Randomized Clinical Trials to Real‐World Data: The INVESTED‐Medicare Linkage Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Real‐world evidence (RWE) derived from real‐world data (RWD) can complement randomized controlled trials (RCTs), yet the validity of RWD relative to RCT data remains insufficiently characterized. We obtained post hoc consent and linked individual participant data from the US‐based INVESTED trial (2016–2019) with Medicare fee‐for‐service claims (2012 ...
Hanseul Cho   +12 more
wiley   +1 more source

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