Results 221 to 230 of about 6,102,677 (302)

Impact of Single‐Cell RNA Reference Selection for the Deconvolution of Breast Cancer Spatial Transcriptomics Datasets

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Spot‐based spatial transcriptomics (ST) allows for unbiased gene expression analysis within tissue architecture, overcoming the limitations of single‐cell RNA sequencing (scRNA‐seq) by preserving spatial context. However, the high spatial resolution in ST leads to cellular heterogeneity within spots, requiring computational deconvolution to ...
Stefan Altendorfer   +2 more
wiley   +1 more source

Optimal timing for induction of labor in normotensive women: A retrospective cohort study

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 365-371, April 2025.
Abstract Objective Labor induction is offered to reduce the risk of stillbirth at late term (41+0 to 41+6) but earlier induction in normotensive singleton pregnancies is supported by weak evidence. The aim of the present study was to investigate the optimal timing for induction in normotensive women.
Jóhanna Gunnarsdóttir   +3 more
wiley   +1 more source

Posttraumatic stress disorder 2 months after induced vaginal delivery: A multicenter prospective study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objectives An increased risk of postpartum posttraumatic stress disorder (PTSD) has been reported in women who had labor induced. Knowledge of childbirth‐related PTSD in this context remain poorly documented. Our aim was to assess the PTSD prevalence and identify characteristics associated with it after induced vaginal delivery at or near term.
Alizée Froeliger   +26 more
wiley   +1 more source

Occult serous tubal intraepithelial carcinoma and high‐grade serous carcinoma at risk‐reducing salpingo‐oophorectomy in BRCA1/2 carriers: A Czech two‐center cohort

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Risk‐reducing salpingo‐oophorectomy is the standard intervention for prevention of tubo‐ovarian carcinoma in women with pathogenic BRCA1/2 variants, yet the optimal timing remains clinically challenging, particularly for BRCA2 carriers.
Olga Zikan Dubova   +4 more
wiley   +1 more source

Conserved SERPINE2 function maintains ovarian estrogen production to support fertility in goats and mice

open access: yesiMetaOmics, EarlyView.
Single‐nucleus RNA sequencing and functional profiling of goat ovaries with divergent litter sizes revealed prolificacy‐associated granulosa cell (GC) states characterized by enhanced proliferation‐ and steroidogenesis‐related features, together with altered predicted cell–cell communication.
Sanbao Zhang   +6 more
wiley   +1 more source

When free is not costless: Mobility, stigma, and zero‐price demand in food banks

open access: yesJournal of the Agricultural and Applied Economics Association, EarlyView.
Abstract This paper examines how demand responds when the monetary price of goods is permanently set to zero, using food bank visitation in Québec (2022–2025). We develop a behavioral full‐price framework in which access is mediated by mobility and social constraints. Using a balanced panel of 19 regions and Poisson pseudo‐maximum likelihood estimation
Tiloux Soundja, Karima Afif
wiley   +1 more source

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