Results 101 to 110 of about 16,853,352 (261)
Switching gears: reforming negative gearing to solve our housing affordability crisis [PDF]
, 2015 This report attempts to break the current political impasse by provide a range of politically pragmatic proposals that would reform negative gearing without abolishing it outright.
Richard Holden
core
Oscillatory mixed difference systems [PDF]
, 2006 The aim of this paper is to discuss the oscillatory behavior of difference systems of mixed type. Several criteria for oscillations are obtained. Particular results are included in regard to scalar equations. Copyright © 2006 J. M.
Ferreira, José M. +4 more
core +2 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Neurotoxic effect of aqueous extract of boldo (Peumus boldus) in an animal model
Revista Peruana de Medicina Experimental y Salud Pública, 2014 Objectives. To assess the neurotoxic effect of the aqueous extract of boldo (Peumus boldus) in an experimental model. Materials and methods. 20 male Holtzman rats of 250 ± 15 g were randomized into four groups: the negative control received saline ...
Jhon William Mejía-Dolores +6 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Evaluation of ototoxic and neurotoxic effects of local diclofenac sodium application
The Egyptian Journal of OtolaryngologyBackground We aimed to investigate diclofenac sodium’s ototoxic and neurotoxic effects, which have already been shown to have a cytotoxic effect on cholesteatoma. Material and methods The subjects were divided into three groups: negative control group (S)
Halil Elden +7 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Bihdād, 2014 Background & Aims: colonized by staphylococcus aureus were reported in more than 50% of psoriatic lesions. Due to role of epidermal barrier dysfunction on colonization and on the other hands staphylococcal super antigen effect on flare up of disease ...
A. Darjani +2 more
doaj
Diyala Journal of Engineering SciencesThis numerical study was conducted to evaluate the effect of longitudinal hollow openings in reinforced concrete beams. The study was divided into three groups: The first group: was circular holes of different sizes.
Haitham Jameel Abd
doaj +1 more source