Results 51 to 60 of about 3,677,885 (302)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Constitutional guarantees generate negative externalities for the brazilian health system
Cadernos Ibero-Americanos de Direito Sanitário, 2017 Objective: we aimed toknowthelegal demandson healthand the arguments made by the patient, the defense, and the judge in judicial hearings. Methods: For this,we used themethodofcase lawresearch.
Maria Celia Delduque
doaj +5 more sources
Disentangling the rhetoric of public goods from their externalities: The case of climate engineering
Global Transitions, 2019 Public goods are defined by the technical conditions of nonexclusion and nonrivalry. Nonetheless, public goods are frequently viewed in environmental policy and scholarly debates as providing strictly positive benefits (or, in the case of public ‘bads ...
Robert Holahan, Prakash Kashwan
doaj +1 more source
MONETIZATION OF ENVIRONMENTAL EXTERNALITIES FOR ECONOMIC ANALYSIS. CASE STUDY: URBAN MOBILITY IN ORADEA [PDF]
Annals of the University of Oradea: Economic Science, 2021 One of the main limitations identified in the specialized literature is represented by the insufficient quantification of the environmental externalities in the process of carrying out the economic analysis within the cost-benefit analysis for the urban ...
Ovidiu – Vasile GULER, Corina BOLOȘ
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Computational Aspects of Extending the Shapley Value to Coalitional Games with Externalities
, 2010 Until recently, computational aspects of the Shapley value were only studied under the assumption that there are no externalities from coalition formation, i.e., that the value of any coalition is independent of other coalitions in the system.
Rahwan, Talal +4 more
core +1 more source
PROPERTY RIGHTS AND THE PROBLEM OF EXTERNALITIES
Электронное приложение к Российскому юридическому журналу, 2019 The article discusses the concept of externalities as one of the key categories of the economic analysis of property rights. Based on a number of scientific publications by R.
Sergeev Andrei
doaj +1 more source