Results 101 to 110 of about 6,038 (295)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

The hidden societal cost of antibiotic resistance per antibiotic prescribed in the United States: an exploratory analysis

BMC Infectious Diseases, 2016
Background Ambulatory antibiotic prescribing contributes to the development of antibiotic resistance and increases societal costs. Here, we estimate the hidden societal cost of antibiotic resistance per antibiotic prescribed in the United States. Methods
Constantinos I. Michaelidis, Michael J. Fine, Chyongchiou Jeng Lin, Jeffrey A. Linder, Mary Patricia Nowalk, Ryan K. Shields, Richard K. Zimmerman, Kenneth J. Smith   +7 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Negative Externalities, Environmental Quality and the Transformation Space [PDF]

, 1982
The purpose of this paper is to analyze the properties of the transformation space of an economy with private goods, environmental quality, and negative externalities. The property of the transformation space determines the level of permissible decentralization [Laffont].
openaire   +2 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Positive And Negative Externality Effects On Product Pricing And Capacity Planning

, 1996
Physically constrained subscription-based telephone network services can experience opposing market forces which affect new product adoption. In such networks, a positive externality due to increases in subscribership encourages more consumers to sign up.
Susan Y. Chao
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Placing the poor while keeping the rich in their place: Separating strategies for optimally managing residential mobility and assimilation

Demographic Research, 2005
A central objective of modern US housing policy is deconcentrating poverty through "housing mobility programs" that move poor families into middle class neighborhoods. Pursuing these policies too aggressively risks inducing middle class flight, but being
Gustav Feichtinger, Dieter Grass, Michael Johnson, Gernot Tragler, Yuri Yegorov, Jonathan P. Caulkins   +5 more
doaj  

Sustainability Analysis of Coffee Farming in Protected Forestof West Lampung Based on Enviromental Economic Value

Coffee and Cocoa Research Journal, 2010
Study on sustainability of multistrata coffee systems is important related to community forest program. This research aims to study: (1) sustainability of coffee farming in protected forest of West Lampung (2) willingness to pay the external cost and its
Fembriarti Erry Prasmatiwi, Irham Irham, Any Suryantini, Jamhari Jamhari   +3 more
doaj   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source