Biotechnology and Bioengineering, EarlyView.ABSTRACT Protein aggregation poses a significant risk to biopharmaceutical product quality, as even minor amounts of oligomeric species can compromise efficacy and safety. Rapid and reliable detection of protein aggregates thus remains a major challenge in biopharmaceutical manufacturing.
Jakob Heyer‐Müller +4 more
wiley +1 more source
Prevalence of burnout and contributing factors among physicians in Burundi: A cross-sectional study. [PDF]
S Afr J PsychiatrNduwimana I, Ntawuyamara E, Zhang G.
europepmc +1 more source
Transfer Learning Approaches in Bioprocess Engineering: Opportunities and Challenges
Biotechnology and Bioengineering, EarlyView.ABSTRACT Transfer learning (TL) has recently emerged as a promising approach to overcoming one of the key limitations of bioprocess engineering: data scarcity. By leveraging knowledge from one bioprocess to another, TL allows existing models and data sets to be reused efficiently, accelerating process development, improving prediction accuracy, and ...
Daniel Barón Díaz +3 more
wiley +1 more source
Additive value of early-phase β-Amyloid-PET for the differential diagnosis of non-Alzheimer's disease dementia. [PDF]
Neuroimage ClinEckenweber S +21 more
europepmc +1 more source
Real‐Time Monitoring of In Vitro Transcription for Production of mRNA Using Raman Spectroscopy
Biotechnology and Bioengineering, EarlyView.Schematic depicting the workflow for model building and validation using Raman spectroscopy for real‐time monitoring of IVT. ABSTRACT The success of COVID‐19 mRNA vaccines showcased the transformative potential of this adaptable, plug‐and‐play, and rapid response platform.
Julia Puppin Chaves Fulber +4 more
wiley +1 more source
What Value Do Dutch Citizens Place on Health Interventions That Provide Greater Health Gains to Lower-Income Groups? A Discrete Choice Experiment. [PDF]
Int J Health Policy ManagMeulman I +5 more
europepmc +1 more source
Mid‐Domain Effect and Wooded Habitat Shape Mediterranean Reptile Communities
Biological Diversity, EarlyView.Analyzing a large number of reptiles observed across protected areas in Central Italy, we tested whether the mid‐domain effect explains hump‐shaped richness–elevation patterns. Species richness was best predicted by the combined influence of geometric constraints and woodland cover, revealing two contrasting species clusters and offering a robust ...
Daniele Dendi +3 more
wiley +1 more source
Circadian syndrome (CircS) and cognitive trajectory deterioration in middle-aged and older adults: A national cohort study with causal forest analysis. [PDF]
Alzheimers DementMa J, Chen N, Huang J, Xu L, Shang H.
europepmc +1 more source
Funding Costs and Liquidity Creation: Does ESG Play Any Role?
Business Strategy and the Environment, EarlyView.ABSTRACT This study examines how banks' funding costs affect liquidity creation and whether environmental, social, and governance (ESG) performance shapes this relationship. Using panel data for 136 U.S. commercial banks from 2005 to 2022, we show that higher funding costs are associated with lower liquidity creation, indicating that more expensive ...
Sattam Bin Kowibeen +2 more
wiley +1 more source
Psychotic Spectrum Symptoms in Adults with Autism Spectrum Disorder and in Their First-Degree Relatives. [PDF]
Brain SciNardi B +9 more
europepmc +1 more source