Results 161 to 170 of about 421,473 (291)

Systematically Engineering for Efficient Production of 3‐Methyl‐1‐Butanol in Escherichia coli

open access: yesAdvanced Science, EarlyView.
An integrated metabolic engineering strategy was established for high‐level 3‐methyl‐1‐butanol biosynthesis in Escherichia coli. Molecular dynamics‐guided semi‐rational engineering of dihydroxyacid dehydratase uncovered and relieved key catalytic bottlenecks, while adaptive laboratory evolution enhanced strain robustness.
Nanfei Geng   +6 more
wiley   +1 more source

Growth‐Like Swelling of 2D Precursors for Efficient Fabrication of Complex 3D Microstructures

open access: yesAdvanced Science, EarlyView.
The growth‐like swelling process fills photocured polymers into the elastomeric microstructures, inducing a significant swelling deformation of microstructures that can be maintained in the absence of solvents. The growth‐like swelling process breaks through the dependence of swelling deformation on the solvents, thereby expanding the application of 3D
Xinkai Zhu   +13 more
wiley   +1 more source

Selectivity Filter Dynamics Define Ion Conductance and Selectivity Differences in CNG and HCN Channels

open access: yesAdvanced Science, EarlyView.
Cyclic nucleotide‐gated (CNG) and hyperpolarization‐activated cyclic nucleotide‐gated (HCN) channels share substantial sequence and structural similarity but differ markedly in ion conductance and K+ selectivity. Microsecond‐scale atomistic MD simulations qualitatively reproduced the conductance differences observed in single‐channel recordings and ...
Haoran Liu   +3 more
wiley   +1 more source

Real‐Time Digital Micromotor Tracking‐Enabled Ultrasensitive Immunoassay

open access: yesAdvanced Science, EarlyView.
An AI‐facilitated real‐time digital micromotor tracking‐enabled immunoassay is developed, which leverages a self‐developed multi‐microparticle tracking system to monitor micromotor motion trajectories in a real‐time manner for digital protein analysis.
Jingjing Shi   +6 more
wiley   +1 more source

Negative Poisson’s Ratio Materials via Isotropic Interactions [PDF]

open access: green, 2008
Mikael C. Rechtsman   +2 more
openalex   +1 more source

Smart Energy–Harvesting Coating for Moisture–Droplets Based on Ionic Diodes and Transistor–Like Structures

open access: yesAdvanced Science, EarlyView.
A smart power‐generating coating is developed to harvest energy from both ambient humidity and impacting liquid droplets. The integrated system delivers sustained open‐circuit voltages of 0.85 V from moisture and up to 36 V from droplets. Its scalable coating architecture enables a continuous power supply for low‐power electronic devices.
Liang Ma   +5 more
wiley   +1 more source

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