Results 71 to 80 of about 144,272 (327)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
An expletive negation unlike any other in Québec French
Isogloss, 2022 This paper explores ‘expletive’ uses of the negative marker pas in Québec French (QF) (Kemp 1982, Larriv´ee 1996), which despite checking every diagnostic for expletive negation (ExN), do not pattern with previously documented cases of ExN.
Aurore Gonzalez, Justin Royer
doaj +1 more source
When negation is not negation [PDF]
, 2008 In this paper I will discuss the formation of different types of yes/no questions in Serbian (examples in (1)), focusing on the syntactically and semantically puzzling example (1d), which involves the negative auxiliary inversion.
Milicevic, Nataša
core
Crowdsourcing a Word-Emotion Association Lexicon [PDF]
, 2012 Even though considerable attention has been given to the polarity of words (positive and negative) and the creation of large polarity lexicons, research in emotion analysis has had to rely on limited and small emotion lexicons.
Mohammad, Saif M., Turney, Peter D.
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Brain Sciences, 2021 Targeted memory reactivation (TMR) and transcranial direct current stimulation (tDCS) can enhance memory consolidation. It is currently unknown whether TMR reinforced by simultaneous tDCS has superior efficacy.
Médhi Gilson +2 more
doaj +1 more source
Negative Sensitive Indefinites in Maltese [PDF]
, 2017 This paper looks at sentential negation in Maltese and the syntactic be- haviour of a group of negative sensitive indefinite items in Maltese, for which existing literature offers only a partial (and indeed partially incorrect) charac- terisation.
Camilleri, Maris, Sadler, Louisa
core
Processing Negative Polarity Items in Korean: Implications from an ERP Study
, 2020 We are grateful to the three anonymous reviewers of this journal for the helpful comments and suggestions. Usual disclaimers apply here, of course. This work was supported by the Ministry of Education of the Republic of Korea and the National Research ...
Myungkwan Park, Eunjeong Oh, Wonil Chung
semanticscholar +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Exclamative Wh-Phrases as Positive Polarity Items
Catalan Journal of Linguistics, 2008 This paper studies the island effects induced by negation in exclamative sentences. In order to explain this phenomenon, I focus on the interaction between exclamative wh-phrases and negation, showing that negation can appear in exclamative sentences ...
Raquel González Rodríguez
doaj +1 more source