Results 181 to 190 of about 3,708,738 (393)

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

Molecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar, Shima Shahbaz, Anthea C. Peters, Spencer B. Gibson, Shokrollah Elahi   +4 more
wiley   +1 more source

Sentence-level quality estimation by predicting HTER as a multi-component metric [PDF]

arXiv, 2017
This submission investigates alternative machine learning models for predicting the HTER score on the sentence level. Instead of directly predicting the HTER score, we suggest a model that jointly predicts the amount of the 4 distinct post-editing operations, which are then used to calculate the HTER score.
arxiv  

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Visual Scoring of Sacroiliac Joint/Sacrum Ratios of Single-Photon Emission Computed Tomography/Computed Tomography Images Affords High Sensitivity and Negative Predictive Value in Axial Spondyloarthritis. [PDF]

Diagnostics (Basel), 2023
Yoon EC, Kim JS, Lim CH, Park SB, Park S, Lee KA, Kim HS.   +6 more
europepmc   +1 more source

Positive and negative predictive values from published studies can be misleading for decision-making in clinical practice [PDF]

, 2006
Martín Rudwaleit, Joachim Sieper
openalex   +1 more source

The Value of Suction Drainage Fluid Culture during Aseptic and Septic Orthopedic Surgery: A Prospective Study of 901 Patients [PDF]

, 2017
There are no guidelines on the value of suction drainage fluid culture (SDC), and it is difficult to determine whether the organisms cultured from suction drainage fluid samples are pathogenic or simply contaminants. We performed 2989 cultures of suction
Bernard, L., Denormandie, P., Feron, J. M., Gaillard, J. L., Gleizes, V., Perrone, C., Pron, B., Si-Ali, A., Signoret, F., Vuagnat, A.   +9 more
core  

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

Molecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti, Shingo Inagaki, Tuyen Thuy Bich Ho, Akihiro Seki, Keiko Yoshida, Kosuke Satomura, Yoshio Sakai, Shuichi Kaneko, Taro Yamashita   +8 more
wiley   +1 more source

Quantification of Metamorphopsia in Resolved Idiopathic Central Serous Chorioretinopathy: An Analysis Using M-CHARTS, Amsler Grid, and Optical Coherence Tomography

Clinical Ophthalmology
Barsha Suwal,1 Deepak Khadka,1 Arjun Shrestha,1 Rinkal Suwal,2 Bijay Khatri3 1Department of Ophthalmology, BP Eye Foundation, Hospital for Children, Eye, ENT, and Rehabilitation Services, Bhaktapur, Nepal; 2Department of Optometry, BP Eye Foundation ...
Suwal B, Khadka D, Shrestha A, Suwal R, Khatri B   +4 more
doaj  

The Paris System for reporting urinary cytology improves the negative predictive value of high-grade urothelial carcinoma. [PDF]

BMC Urol, 2022
Yamasaki M, Taoka R, Katakura K, Matsunaga T, Kani N, Honda T, Harada S, Tohi Y, Matsuoka Y, Kato T, Okazoe H, Tsunemori H, Ueda N, Haba R, Sugimoto M.   +14 more
europepmc   +1 more source

Positive and negative predictive values from published studies can be misleading for decision-making in clinical practice: reply [PDF]

, 2006
Christina Duftner, Christian Dejaco, Michael Schirmer   +2 more
openalex   +1 more source