Results 201 to 210 of about 1,586,154 (340)

Value of HPV 16/18 Genotyping and p16/Ki-67 Dual Staining to Predict Progression to HSIL/CIN2+ in Negative Cytologies From a Colposcopy Referral Population [PDF]

, 2018
Adriano Rodríguez‐Trujillo, Cristina Martí, Martina Aida Ángeles, A. de la Sierra, Roser Esteve, Adela Saco, Esther Barnadas, Lorena Marimón, Inmaculada Nicolás, Aureli Torné, Jaume Ordï, Marta del Pino   +11 more
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Negative Predictive Value of a Prostate MRI in Black Men: Implications for Biopsy Decision-Making. [PDF]

J Urol
Sandlow S, Carbunaru S, Sun Z, Ofori B, Liu Y, Li E, Hollowell CMP, Vidal P, Perry KT, Patel HD, Dobbs RW, Casalino DD, Wood CG, Jawahar A, Amarasekera C, Horowitz JM, Miller FH, Gumusgoz E, Yang XJ, Choy B, Manosca F, Bagci U, Schaeffer EM, Gann P, French DD, Ross AE, Kundu SD, Murphy AB.   +27 more
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Negative Predictive Value (NPV) [PDF]

, 2019
openaire   +1 more source

Metagenomic analysis of NIPT raw data suggests high negative predictive value for congenital cytomegalovirus infection screening [PDF]

Nicolas Bourgon, Ismaël Padioleau, Julie Guibon, Jacques Fourgeaud, Alban Lermine, Guillaume Meurice, Tiffany Guilleminot, L. Bussières, Marianne Leruez‐Ville, Jean‐Michel Dupont, Y. Ville   +10 more
openalex   +1 more source

Predictive value of FibroScan in detecting liver fibrosis in HBeAg negative patients with chronic hepatitis B whose HBV DNA 2000-20000 IU/ml with ALT 1-2 times the upper limit of normal and those with HBV DNA >20000 IU/ml and normal ALT

, 2021
Nilay Danış
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Negative predictive value of fecal immunochemical testing in significant bowel disease screening: a systematic review and meta-analysis. [PDF]

Int J Surg
Junhai Z, Fei L, Jixiang Z, Huabing X, Cheng T, Weiguo D.   +5 more
europepmc   +1 more source

Positive and negative predictive value of ultrasonography in diagnosis of breast cancer in patients with nipple discharge

, 2013
Haesung Yoon
openalex   +1 more source