Results 221 to 230 of about 1,586,154 (340)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Predictive value and clinical utility of centrally assessed ER, PgR, and Ki-67 to select adjuvant endocrine therapy for premenopausal women with hormone receptor-positive, HER2-negative early breast cancer: TEXT and SOFT trials

, 2015
Meredith M. Regan, Olivia Pagani, Prudence A. Francis, Gini F. Fleming, Barbara Walley, Roswitha Kammler, Patrizia Dell’Orto, Leila Russo, János Szőke, Franco D. Doimi, Laura Villani, Stefano Pizzolitto, Christian Öhlschlegel, Fausto Sessa, V. Peg Cámara, José Luis Rodríguez‐­Peralto, Gaëtan MacGrogan, Marco Colleoni, Aron Goldhirsch, Karen N. Price, Alan S. Coates, Richard D. Gelber, Giuseppe Viale, Giuseppe Viale   +23 more
openalex   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Negative predictive values for three main groups of medicaments for quickly resolve food allergic reactions in children [PDF]

, 2011
Adnan Bajraktarević, Andrea Pahor Kurilic, S Putica, Begeler Begovic, Amina Selimović, Asmir Musabegovic, Teodora Frankic, Haris Nikšić, Nermina Korac, Aida Djulepa Djurdjevic, Branka Djukic, Lutvo Sporpsevic   +11 more
openalex   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Negative Predictive Value of Ultrasound in Evaluation of Malignancy in Hypofunctioning Thyroid Nodules [PDF]

, 2016
Kim Xia
openalex   +1 more source

Reconstitution of double-negative T cells after cord blood transplantation and its predictive value for acute graft-versus-host disease

, 2023
Tianzhong Pan, Peng Ding, Aijie Huang, Baolin Tang, Kaidi Song, Guangyu Sun, Yue Wu, Shiying Yang, Xingchi Chen, Dongyao Wang, Xiaoyu Zhu   +10 more
openalex   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source