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Prevalence of Primary, Prominent, and Predominant Negative Symptoms of Schizophrenia in Routine Inpatient Psychiatric Care [PDF]
Background and Objectives: Prevalence data of different classes of negative symptoms in an inpatient setting are scarce. Most of the data are collected in clinical trials under strict inclusion criteria, using older psychometric scales with known content
Jonas Montvidas +4 more
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Negative symptoms in schizophrenia
The negative symptoms have been described in association with schizophrenia since the early days of it being recognized as an entity. However, their elusive nature kept them unacknowledged until there was a revival of interest in them following the ...
Sayantanava Mitra +3 more
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New treatment perspectives for negative symptoms [PDF]
Introduction Persistent negative symptoms of schizophrenia are generally considered difficult to treat or treatment resistant. A large number of investigational drugs developed and or tested for the treatment of persistent negative symptoms failed to ...
I. Bitter
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Effectiveness of spironolactone on schizophrenia symptoms: A double-blind randomized clinical trial [PDF]
Introduction: Schizophrenia is a mental disorder in which the facts surrounding a person are interpreted as abnormal. The treatment aims to reduce symptoms and the possibility of disease recurrence. Aim: This study aimed to investigate the effectiveness
Nazanin Hoghoughi +4 more
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EPA guidance on assessment of negative symptoms in schizophrenia
BackgroundDuring the last decades, a renewed interest for negative symptoms (NS) was brought about by the increased awareness that they interfere severely with real-life functioning, particularly when they are primary and persistent.MethodsIn this ...
S. Galderisi +13 more
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Negative symptoms are considered a core feature of schizophrenia. They are present since the prodromal phase and tend to persist more than other psychopathological dimensions in the chronic stages.
A. Mucci +4 more
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Negative and Cognitive Symptoms of Schizophrenia: Are there Adequate Pharmacological Treatments?
Introduction The ongoing debate regarding the treatment efficacy for negative and cognitive symptoms in schizophrenia is a subject of continuous frustration among psychiatrists.
O. Vasiliu
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Adjunctive simvastatin treatment in schizophrenia patients; a double blind randomized and placebo controlled trial [PDF]
Introduction: Statins such as simvastatin are recently introduced as agents that may have beneficial effects in schizophrenia regarding their prominent anti-inflammatory properties.
Somaieh Ashrafi +6 more
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Primary and Secondary Negative Symptoms in Schizophrenia
The negative symptoms of schizophrenia include volitional (motivational) impairment manifesting as avolition, anhedonia, social withdrawal, and emotional disorders such as alogia and affective flattening.
Sergey N. Mosolov +2 more
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Management of cognitive and negative symptoms in schizophrenia [PDF]
Currently available antipsychotics provide only modest benefit in managing the cognitive and negative symptoms of schizophrenia even though these symptoms are often the most impairing in patients daily lives.
Megan Maroney, PharmD, BCPP
doaj +1 more source

