Results 91 to 100 of about 455,043 (294)

Covalent Inhibitors for Neglected Diseases: An Exploration of Novel Therapeutic Options. [PDF]

Pharmaceuticals (Basel), 2023
Alves ETM, Pernichelle FG, Nascimento LA, Ferreira GM, Ferreira EI.   +4 more
europepmc   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Correction: Head Lice of Pygmies Reveal the Presence of Relapsing Fever Borreliae in the Republic of Congo.

PLoS Neglected Tropical Diseases
[This corrects the article DOI: 10.1371/journal.pntd.0005142.].
PLOS Neglected Tropical Diseases Editors
doaj   +1 more source

Guinea Worm Disease: A Neglected Diseases on the Verge of Eradication. [PDF]

Trop Med Infect Dis, 2022
Pellegrino C, Patti G, Camporeale M, Belati A, Novara R, Papagni R, Frallonardo L, Diella L, Guido G, De Vita E, Totaro V, Segala FV, Veronese N, Cotugno S, Bavaro DF, Putoto G, Bevilacqua N, Castellani C, Nicastri E, Saracino A, Di Gennaro F.   +20 more
europepmc   +1 more source

Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay

Advanced Science, EarlyView.
This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao, Ruiqi Zhang, Rujun Wei, Huimin Fan, Yongfei Hu, Wenyu Shi, Jinfeng Wang   +6 more
wiley   +1 more source

Correction: Schistosoma japonicum cathepsin L1: A potential target for anti-schistosomiasis strategies.

PLoS Neglected Tropical Diseases
[This corrects the article DOI: 10.1371/journal.pntd.0013241.].
PLOS Neglected Tropical Diseases Staff
doaj   +1 more source

Editorial: One Health Approach in Zoonosis: strategies to control, diagnose and treat neglected diseases. [PDF]

Front Cell Infect Microbiol, 2023
Quaresma PF, Martins-Duarte ES, Soares Medeiros LC.   +2 more
europepmc   +1 more source

Multicohort Validation of Gut Microbiome Signatures for Cholangiocarcinoma Diagnosis and Functional Characterization of Bifidobacterium Pseudocatenulatum

Advanced Science, EarlyView.
This study analyzes gut bacteria in cholangiocarcinoma patients, revealing distinct microbial signatures that enable accurate disease detection. Species‐based diagnostic models achieved over 98% accuracy in identifying cholangiocarcinoma and distinguished it from other liver diseases. The research demonstrates that specific beneficial bacteria suppress
Benchen Rao, Jianwen Jiang, Ruiqing Zhang, Dongya Zhang, Chenchen Zhang, Ang Li, Haifeng Lu, Hua Zhang, Lin Zhou, Wenzhi Guo, Peihao Wen, Jianfeng Xue, Jie Pan, Tuerganaili Aji, Zhou Lan, Xianzhi Jiang, Shusen Zheng, Zujiang Yu, Zhigang Ren   +18 more
wiley   +1 more source

Correction: Insights into the Interactions of Fasciola hepatica Cathepsin L3 with a Substrate and Potential Novel Inhibitors through In Silico Approaches. [PDF]

PLoS Neglected Tropical Diseases, 2015
PLOS Neglected Tropical Diseases Staff
doaj   +1 more source

COVID-19 vaccines and the pandemic: lessons learnt for other neglected diseases and future threats. [PDF]

BMJ Glob Health, 2023
Hotez PJ, Gilbert S, Saville M, Privor-Dumm L, Abdool-Karim S, Thompson D, Excler JL, Kim JH.   +7 more
europepmc   +1 more source