Results 261 to 270 of about 458,223 (349)

Challenges and Opportunities in Repurposing Natural Products for the Treatment of Neglected Trophical Diseases: A Review of Scaffold Optimization Strategies

Musa Yahaya Abubakar, Tony Mathew, Ruslan Shamsuddeen, S. Abdullahi, Ansar Bilyamin, Emmanuel K. Chinedu   +5 more
openalex   +2 more sources

BRICS in the response to neglected tropical diseases

, 2014
Amber Cashwell, Anupama Tantri, Ashley Schmidt, G. Simon, Neeraj Mistry   +4 more
openalex   +1 more source

Fibroblast Transcriptomics in Molecular Diagnostics of a Comprehensive Dystonia Cohort

Annals of Neurology, EarlyView.
Objective Genomic sequencing leaves >50% of dystonia‐affected individuals without a diagnosis. Where DNA‐oriented approaches remain insufficient, integrating multiomics is essential to advance genome interpretation. Herein, we incorporated RNA sequencing (RNA‐seq) data from 167 patients with dystonia across a range of ages and presentations. Methods We
Alice Saparov, Ivana Dzinovic, Theresa Brunet, Vicente A. Yépez, Florian Hölzlwimmer, Elisabetta Indelicato, Birgit Assmann, Susann Badmann, Diana Ballhausen, Steffen Berweck, Felix Brechtmann, Melanie Brugger, Kevork Derderian, Felix Distelmaier, Philip Harrer, Denisa Harvanova, Petra Havrankova, Ann‐Kathrin Jaroszynski, Miriam Kolnikova, Robert Kopajtich, Anne Koy, Magdalena Krygier, Lukas Kunc, Katarina Kusikova, Oliver Maier, Maria Mazurkiewicz‐Bełdzińska, Christian Mertes, Ava Oberlack, Timo Roser, Alexandra Sitzberger, Ugo Sorrentino, Antonia M. Stehr, Katharina Vill, Matias Wagner, Holger Prokisch, Sylvia Boesch, Jan Necpal, Robert Jech, Juliane Winkelmann, Elisabeth Graf, Julien Gagneur, Matej Skorvanek, Michael Zech   +42 more
wiley   +1 more source

The need for a balance between highly prevalent diseases and neglected diseases. [PDF]

J Bras Pneumol, 2018
Souza R.
europepmc   +1 more source

Uncommon and Neglected Venezuelan Viral Diseases: Etiologic Agents, Physiopathological, Clinical and Epidemiological Characteristics

, 2015
Juan Carlos Gabaldón-Figueira, Siham Salmen, Guillermo Terán‐Ángel   +2 more
openalex   +1 more source

PLOS Neglected Tropical Diseases 2016 Reviewer and Editorial Board Thank You

, 2017

openalex   +2 more sources

Distinct Prescription Patterns Emerge Years Before ALS Diagnosis: A Nationwide Registry‐Based Study

Annals of Neurology, EarlyView.
Objective The prodromal phase of amyotrophic lateral sclerosis (ALS) is poorly defined. We aimed to characterize prescription drug use patterns in the pre‐diagnostic period by analyzing nationwide prescription data to identify the earliest divergence between individuals who developed ALS and matched healthy controls.
Magne Haugland Solheim, Trond Riise, Marianna Cortese, Ola Nakken, Ole‐Bjørn Tysnes, Jannicke Igland, Kjetil Bjornevik   +6 more
wiley   +1 more source

Aggregation‐State Dynamics Drive Double Cooperativity Between Antimicrobial Peptides LL‐37 and HNP1

Angewandte Chemie, EarlyView.
The double cooperative effect between LL‐37 and HNP1 arises from dynamic changes in their aggregation state. These LL‐37/HNP1 assemblies reorganize in a target‐dependent manner, suppressing activity toward mammalian cells while enabling potent antibacterial action.
Yuge Hou, Jing Zhang, Koh Takeuchi, Hideo Higuchi, Motoshi Kaya, Rui Li, Jianlu Zheng, Jiali Chen, Go Watanabe, Kaori Sugihara   +9 more
wiley   +2 more sources

Don't Neglect the Neglected Tropical Diseases [PDF]

Cambridge Medicine Journal, 2012
openaire   +1 more source

Tungiasis: a highly neglected disease among neglected diseases. Case series from Nduta refugee camp (Tanzania). [PDF]

Oxf Med Case Reports, 2019
Nájera Villagrana SM, García Naranjo Santisteban A.   +1 more
europepmc   +1 more source