Results 231 to 240 of about 3,023,382 (303)

Confronting neglected tropical diseases: a moral and strategic imperative for global equity. [PDF]

Infect Dis Poverty
Engels D, Zhou XN.
europepmc   +1 more source

Synthesis, Antiparasitic Activity, and ADME Profile of Morpholinephenylbenzamides: A Pharmacological Study Against Chagas Disease and Visceral Leishmaniasis

ChemMedChem, Volume 21, Issue 19, 14 October 2026.
Hit‐to‐lead optimization of morpholinephenylbenzamides reveals key structure–activity relationships against Trypanosoma cruzi and Leishmania infantum. Potency, selectivity, and ADME properties are differentially improved across the series, identifying compounds 20, 24, and 16 as complementary templates for the future design of dual antiparasitic leads.
Danilo Nascimento Farago, Daniela de Melo Resende, Mariza Gabriela Faleiro de Moura Lodi Cruz, Rafaela Marçal Sousa, Rafael Consolin Chelucci, Simone Michelan‐Duarte, Felipe da Silva Mendonça de Melo, Douglas Davison da Silva Oliveira, Paula Derksen Macruz, Alexandra Maria dos Santos Carvalho, Eduardo Jorge Pilau, Izabela Marques Dourado Bastos, Adriano D. Andricopulo, Leonardo L. G. Ferreira, Silvane Maria Fonseca Murta, Celso de Oliveira Rezende Júnior   +15 more
wiley   +1 more source

Zoonotic neglected tropical diseases at the animal-human interface in the Greater Mekong Subregion: Two decades of surveillance in Laos and Cambodia. [PDF]

PLoS Negl Trop Dis
Blacksell SD, Ward MP, Young JR, Bush RD, Windsor PA, Khounsy S, Phommachanh P, Theppangna W, Siengsanan-Lamont J, Burns R, Turner P, Gilbert J, Kong L, Tum S, Karlsson EA, Conlan JV, Hughes T, Kolenchery JB, Roberts T, Robinson MT, Vongsouvath M, Newton PN, Mayxay M, Ashley EA, Day NPJ.   +24 more
europepmc   +1 more source

Socio‐Economic and Ecological Drivers of the Spread of Non‐Native Tilapia (Oreochromis niloticus) Species in Kenya

Aquaculture, Fish and Fisheries, Volume 6, Issue 5, October 2026.
ABSTRACT Nile tilapia (Oreochromis niloticus) is the dominant non‐native fish species in Kenya's inland waters, but its spread reflects a coupled socioecological process rather than a simple biological invasion. This review examines the socio‐economic, governance and ecological drivers of its expansion within a socioecological systems and invasion ...
Otieno Kashim Oginga, Robert Maina Waruiru, Finnan Okoth Ageng'o, Callen Onura, Caroline Jepkorir Kibet   +4 more
wiley   +1 more source

Accelerating vaccine research and development for skin neglected tropical diseases: A case for leishmaniasis, leprosy, and Buruli ulcer. [PDF]

PLoS Negl Trop Dis
Wang H, Novais FO, Gómez MA, Muhi S, de Oliveira CI, Pham TT, Vermaak S, VALIDATE Network Skin NTDs Working Group, Reljic R.   +8 more
europepmc   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, Volume 73, Issue 5, Page 2457-2481, October 2026.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source

Flight of the dragons: a global review of migration in Odonata

Biological Reviews, Volume 101, Issue 5, Page 2134-2157, October 2026.
ABSTRACT Insects are the most abundant and ecologically important animal migrants. Yet, we know relatively little about the patterns and processes underlying insect migration. Dragonflies (Anisoptera) and damselflies (Zygoptera) comprise the ancient insect order Odonata, whose ancestors were the first organisms to fly on Earth.
Johanna S.U. Hedlund, Myles Menz, Jason W. Chapman, Alexander Hayward   +3 more
wiley   +1 more source

Editorial: Emerging and reemerging neglected tropical diseases: their epidemiology, transmission, mitigation, and vaccines and chemotherapeutics advancements, volume II. [PDF]

Front Pharmacol
Mohapatra RK, Mishra S, Kandi V, Mohapatra NP, Sirka CS.   +4 more
europepmc   +1 more source

Orchard netting impacts on biodiversity leading to cascading effects at the ecosystem level

Biological Reviews, Volume 101, Issue 5, Page 2448-2466, October 2026.
ABSTRACT Agriculture must ensure food production without further compromising the ecosystem functions upon which it depends. Agricultural practices should therefore avoid harming farmland biodiversity, especially of taxa that supply the key ecosystem services (e.g.
Corrado Alessandrini, Karan Sethi, Emanuela Granata, Ekaterina Mogilnaia, Valeria Vitangeli, Giovanni Zanfei, Chiara Fedrigotti, Paolo Biella, Dino Scaravelli, Luigi Marchesi, Péter Batáry, Diego Rubolini, Paolo Pedrini, Mattia Brambilla   +13 more
wiley   +1 more source