Results 151 to 160 of about 339 (184)

Filament formation and NAD processing by noncanonical human FAM118 sirtuins. [PDF]

Nat Struct Mol Biol
Baretić D, Missoury S, Patel K, Martinez M, Coste F, Zhu K, Smith R, Kopasz AG, Lu Y, Bigot N, Chapuis C, Riou R, Đukić N, Goffinont S, Pressoir V, Patačko S, Timinszky G, Delarue M, Castaing B, Ahel D, Mikoč A, Huet S, Ahel I, Suskiewicz MJ.   +23 more
europepmc   +1 more source

Revolutionising Agricultural Sustainability: New ‘Furrow Tillage’ can Mitigate Short‐Term Soil‐to‐Atmosphere CO2 Flux and Promote Soil‐Plant‐Microbe Health

Advanced Science, EarlyView.
Furrow tillage resolves the conventional‐vs.‐no‐tillage trade‐off by simultaneously cutting CO2 efflux to 2.0–3.0 g C m−2 d−1 and unlocking high nutrient availability for the rice rhizosphere. This scalable agronomic solution strengthens soil health, enhances plant physiology, reshapes microbial metabolism, and shifts paddy systems toward a net ...
Arnab Majumdar, Munish Kumar Upadhyay, Argha Ghosh, Rakesh Biswas, Ioly Kotta Loizou, Martin Buck, Mark Tibbett, Biswajit Giri, Debojyoti Moulick, Manoj Kumar Jaiswal, Tarit Roychowdhury   +10 more
wiley   +1 more source

Cellograph: a semi-supervised approach to analyzing multi-condition single-cell RNA-sequencing data using graph neural networks. [PDF]

BMC Bioinformatics
Shahir JA, Stanley N, Purvis JE.
europepmc   +1 more source

Identifying a Csmd3+ Microglial Subpopulation that Drives Cold‐to‐Hot Transition and Immune‐Cure in Glioblastoma

Advanced Science, EarlyView.
The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang, Pan‐Pan Gao, Yu‐Wen Du, Li‐Qin Wu, En‐Zhi Yin, Qi An, Ze‐Hua Ding, Jin‐Wen Shi, Ya Shu, Ruoqiao Chen, Feng Liu, Mingfeng Li, Xiao Qian Chen   +12 more
wiley   +1 more source

A Unifying Thermodynamic Model for Phase Separation and Aging of Biopolymers

Advanced Science, EarlyView.
Phase separation and aging of intrinsically disordered proteins are placed in a unifying framework. A thermodynamically consistent time‐dependent version of associating‐polymer theory shows how the processes are intricately coupled. Assuming aging to occur through interacting sites resulting from reversible conformational transitions, the model ...
Jasper J. Michels, Joana Caria, Edward A. Lemke   +2 more
wiley   +1 more source

Integrated spatial proteomic analysis of breast cancer heterogeneity unravels cancer cell phenotypic plasticity. [PDF]

Nat Commun
Mardamshina M, Karagach S, Mohan V, Arad G, Necula D, Golani O, Fellus-Alyagor L, Shenoy A, Krol K, Pirak D, Itzhacky N, Marin I, Shalmon B, Addadi Y, Sharan R, Gal-Yam E, Barshack I, Geiger T.   +17 more
europepmc   +1 more source

Current Challenges of Transcription Compartmentalization Research

Advanced Science, EarlyView.
Transcription factors, coactivators, and RNA polymerase II assemble into transcription compartments ranging from small, defined complexes to liquid‐like condensates. This review unifies these seemingly competing descriptions along a single continuum and asks what these compartments have been shown to do, and what they have not, revealing that the most ...
Thomas Quail, Sina Wittmann
wiley   +1 more source

Genome-based characterization of AHPND and non-AHPND <i>Vibrio campbellii</i> isolates from Republic of Korea. [PDF]

Front Microbiol
Lee SY, Choi HJ, Lee S, Choi J, Kwak JS, Kang YJ, Hong SC.   +6 more
europepmc   +1 more source