Results 91 to 100 of about 53,214 (202)

The lack of specificity of sodC-based PCR for the detection of Neisseria meningitidis carriage in pharyngeal swabs from adolescents

Microbiology Spectrum
The utility of the superoxide dismutase C (sodC) gene for detecting Neisseria meningitidis carriage in pharyngeal swab samples is unclear. While it has been explored as an alternative to the capsule transport A gene for detecting invasive strains, its ...
Dan Duy Pham-Tran, Lex E. X. Leong, Mark McMillan, Andrew Lawrence, Hassen Mohammed, Adam Finn, Helen S. Marshall   +6 more
doaj   +1 more source

Meningococcal arthritis and myopericarditis: a case report

BMC Infectious Diseases, 2017
Background We report the first adult case of Neisseria meningitidis W-135 presenting with meningococcal arthritis and myopericarditis concomitantly, without other classical features of meningococcal disease.
Lloyd Steele, Katie Bechman, Eoghan De Barra, Charles Mackworth-Young   +3 more
doaj   +1 more source

Molecular epidemiology of meningococcal disease in Northern Ghana [PDF]

, 2001
Meningococcal disease remains a major public health concern, especially in the African Meningitis Belt where large meningitis epidemics with attack rates of up to 500/100,000 recur every 8-12 years.
Gagneux, Sébastien
core   +1 more source

Overwhelming Post‐Splenectomy Sepsis From Capnocytophaga canimorsus

International Journal of Laboratory Hematology, EarlyView.
Maitlyn Hsia, Maud Ahmad, Cyrus C. Hsia, Benjamin Chin‐Yee   +3 more
wiley   +1 more source

Nucleases and Their Inhibitors: Exploring Biological Roles, Industrial Applications, and Challenges in Heterologous Expression

Biotechnology Journal, Volume 21, Issue 9, September 2026.
Graphical Abstract and Lay Summary Intracellular nucleases, depicted as blue circles in a nucleosome, hydrolyze phosphodiester bonds, repair damaged DNA using DNA base excision repair (BER), mismatch repair (MMR), and homologous recombination (HR), and are involved in DNA replication.
Wian Vermeulen, Anton Du Preez van Staden, Leon M. T. Dicks   +2 more
wiley   +1 more source

Contribution of receptors to 'Neisseria meningitidis' interactions with human macrophages [PDF]

, 2004
N. meningitidis is a gram-negative human pathogen that invades human cells, evades immune responses and goes on to cause meningococcal disease, sepsis and death.
Abdillahi, Fatumo Abdi
core   +3 more sources

Intraventricular empyema caused by Neisseria meningitidis

IDCases, 2019
Meningitis is defined as an inflammation of the protective covering of brain and spinal cord collectively called as meninges. Meningeal infection can be complicated by intraventricular empyema.
Divyansh Bajaj, Ankit Agrawal, Darshan Gandhi, Reba Varughese, Sonali Gupta, David Regelmann   +5 more
doaj   +1 more source

Cases of Neisseria meningitidis in Greece

Eurosurveillance, 1997
In Greece, Neisseria meningitidis appears as sporadic cases with some seasonal local outbreaks. The notification of meningococcal disease to the local health authorities and the Ministry of Health is mandatory.
J, Kremastinou, G, Tzanakaki, N, Vakalis, A, Velonaki   +3 more
openaire   +2 more sources

A First‐in‐Japanese Phase 1, Double‐Blind, Placebo‐Controlled, Parallel‐Cohort Study of Sefaxersen, an Antisense Oligonucleotide Targeting Complement Factor B, in Healthy Participants

Clinical Pharmacology in Drug Development, Volume 15, Issue 9, September 2026.
Abstract Increased activity in the complement alternative pathway (AP) plays a key role in diseases such as IgA nephropathy (IgAN). This first‐in‐Japanese double‐blind Phase 1 study investigated the pharmacokinetics (PK), pharmacodynamics (PD), safety, and tolerability of sefaxersen (RO7434656), an antisense oligonucleotide targeting complement factor ...
Takakazu Sato, Hiroyuki Fukase, Takaaki Ishida, Arisa Karasawa   +3 more
wiley   +1 more source

Rapid diagnostic testing method to detect ROB β-lactamase gene in Neisseria meningitidis

Molecular and Cellular Probes
blaROB-1 is the only widely found β-lactamase in Neisseria meningitidis, and its presence is on the rise. To enhance our bacterial meningitis testing procedure, we clinically validated a real-time PCR assay to rapidly detect the blaROB gene and predict ...
Andrew Peifer, Anna Kidney, Geetha Nattanmai, Kate Wahl, Sherly Jose, Elizabeth Owuor, Linnell Randall, Erin Klingbeil, Kimberlee A. Musser, Kara Mitchell   +9 more
doaj   +1 more source