LRRK2 kinase activity is necessary for development and regeneration in Nematostella vectensis [PDF]
Background The starlet sea anemone, Nematostella vectensis, is an emerging model organism with a high regenerative capacity, which was recently found to possess an orthologue to the human Leucine Rich Repeat Kinase 2 (LRRK2) gene.
Grace Holmes +3 more
doaj +8 more sources
A novel in vivo system to study coral biomineralization in the starlet sea anemone, Nematostella vectensis [PDF]
Summary: Coral conservation requires a mechanistic understanding of how environmental stresses disrupt biomineralization, but progress has been slow, primarily because corals are not easily amenable to laboratory research.
Brent Foster +6 more
doaj +4 more sources
NvPrdm14d-expressing neural progenitor cells contribute to non-ectodermal neurogenesis in Nematostella vectensis [PDF]
Neurogenesis has been studied extensively in the ectoderm, from which most animals generate the majority of their neurons. Neurogenesis from non-ectodermal tissue is, in contrast, poorly understood.
Quentin I. B. Lemaître +6 more
doaj +4 more sources
An ancient pan-cnidarian microRNA regulates stinging capsule biogenesis in Nematostella vectensis [PDF]
Summary: An ancient evolutionary innovation of a novel cell type, the stinging cell (cnidocyte), appeared >600 million years ago in the phylum Cnidaria (sea anemones, corals, hydroids, and jellyfish).
Arie Fridrich +7 more
doaj +3 more sources
Unique Transcriptional Responses by the Sea Anemone Nematostella vectensis to Individual Bacteria: Roles for Bacterial Species, Secreted Products and the Microbiome. [PDF]
ABSTRACT Animal responses to bacteria, viruses and other microorganisms are important for understanding how host–microbe interactions lead to divergent molecular responses by the host and the assembly of the holobiont. The immune system of the animal and the resident microbial community are critical factors in the response, or lack thereof, by a host ...
Krueger Q, Phippen B, Reitzel AM.
europepmc +2 more sources
Histone demethylase Lsd1 is required for the differentiation of neural cells in Nematostella vectensis [PDF]
The evolutionary point where chromatin modifier function integrated into regulation of specific cell types is unclear. In the cnidarian Nematostella vectensis, the authors here show that lysine specific demethylase Lsd1 is developmentally regulated and ...
James M. Gahan +4 more
doaj +2 more sources
Cellular pathways during spawning induction in the starlet sea anemone Nematostella vectensis [PDF]
In cnidarians, long-term ecological success relies on sexual reproduction. The sea anemone Nematostella vectensis, which has emerged as an important model organism for developmental studies, can be induced for spawning by temperature elevation and light ...
Shelly Reuven +5 more
doaj +2 more sources
Hypoxia Disrupts Sex-Specific Physiology and Gene Expression Leading to Decreased Fitness in the Estuarine Sea Anemone Nematostella vectensis. [PDF]
ABSTRACT Coastal seawater hypoxia is increasing in temperate estuaries under global climate change, yet it is unknown how low oxygen conditions affect most estuarine species. We found that hypoxia has increased since the 1990s in an estuary hosting the sea anemone Nematostella vectensis (Jacques Cousteau National Estuarine Research Reserve, New Jersey,
Glass BH +5 more
europepmc +2 more sources
Large-scale deorphanization of Nematostella vectensis neuropeptide G protein-coupled receptors supports the independent expansion of bilaterian and cnidarian peptidergic systems [PDF]
Neuropeptides are ancient signaling molecules in animals but only few peptide receptors are known outside bilaterians. Cnidarians possess a large number of G protein-coupled receptors (GPCRs) – the most common receptors of bilaterian neuropeptides – but ...
Daniel Thiel +6 more
doaj +2 more sources
Genotype-environment interactions determine microbiota plasticity in the sea anemone Nematostella vectensis. [PDF]
Most multicellular organisms harbor microbial colonizers that provide various benefits to their hosts. Although these microbial communities may be host species- or even genotype-specific, the associated bacterial communities can respond plastically to ...
Laura Baldassarre +2 more
doaj +2 more sources

