Results 211 to 220 of about 11,952,562 (245)

Breast Modular Resection Surgery Teaching Model Improves the Effect of Teaching Under Regional Anesthesia for Breast Conserving Surgery and Sentinel Lymph Node Biopsy in Day Surgery. [PDF]

Health Care Sci
Yao R, Wu A, Lian J, Tan L, Gao L, Pan B, Sun Q, Zhou Y.   +7 more
europepmc   +1 more source

The immunological landscape of the area postrema in neuromyelitis optica spectrum disorders

Brain Pathology, EarlyView.
Aquaporin‐4 antibody‐positive neuromyelitis spectrum disorder is characterized by large tissue destructive lesions in medulla, spinal cord, and optic nerves, with only partial recovery from clinical symptoms, and by lesions with very little tissue destruction and mostly complete recovery from clinical symptoms, as seen in the area postrema ...
Qian Yu, Yoshiki Takai, Naoya Yamazaki, Sarah Brandl, Katharina M. Mair, Thibault Bouderlique, Maria Eleni Kastriti, Igor Adameyko, Romana Höftberger, Markus Reindl, Jan Bauer, Monika Bradl   +11 more
wiley   +1 more source

Targetable alterations and personalized treatment in ameloblastoma: results from a prospective observational precision oncology study. [PDF]

NPJ Precis Oncol
Hofmann E, Abu-Sirhan S, Elsholtz F, Piwonski I, Kreutzer K, Doll C, Joosten M, Möbs M, Busch CJ, Fenske B, Knödler M, Pestana A, Hirschhorn A, Heiland M, Keller U, Keilholz U, Klinghammer K, Rieke DT, Schmidt M.   +18 more
europepmc   +1 more source

Decoding neuronal vulnerability: Multidimensional analysis of D1R‐ and D2R‐ medium‐sized spiny neurons in Huntington's disease

Brain Pathology, EarlyView.
D1R and D2R MSNs show distinct responses to Huntington's pathology. G&T‐sequencing of pre‐symptomatic MSNs reveals global LINE‐1 downregulation. While D1R‐MSNs display early transcriptomic changes (OXPHOS/translation upregulation) and reduced mutant huntingtin aggregation, D2R‐MSNs exhibit higher nuclear mHTT accumulation and greater CAG somatic ...
Guendalina Bergonzoni, Miguel Pellegrini, Aurora Savino, Martina Lazioli, Sarah Geurs, Lorenzo Graziani, Denise Ferrarini, Solaleh Khoramian Tusi, Esaria Oliver, Jarne Geurts, Sara Vinciguerra, Michele Tebaldi, Takshashila Tripathi, Isabella Pesce, Valeria Poli, Alessandro Romanel, Rosario Moratalla, Thierry Voet, Jasmin Morandell, Remo Sanges, Vanessa C. Wheeler, Erik Dassi, Marta Biagioli   +22 more
wiley   +1 more source

Investigating the Triaxial Mechanical Behaviour of Silicone Rubber Material. [PDF]

Polymers (Basel)
Yang J, Chen N, Gao J, Wang Y, Long S, Yao X, Wu Z, Zhao J.   +7 more
europepmc   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Integrated 3D light sheet and 2D multiplex imaging for deep histological characterization of somatic mouse glioblastoma. [PDF]

iScience
Tiveron MC, Coré N, Bigott K, Fontana YH, Caccavale M, Vilvandre L, El Yassouri F, Schoppel V, Rüberg S, Jungblut M, Figarella-Branger D, Tchoghandjian A, Bosio A, Cremer H.   +13 more
europepmc   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Tongue Squamous Cell Carcinoma in a Young Patient Without Classical Risk Factors: A Case Report and Literature Review. [PDF]

Cureus
Moudahik Z, Farih Z, Bououdar K, Khazana M, Naji Y.   +4 more
europepmc   +1 more source

Computational modeling of tissue damage preceding aortic dissection: a coupled biphasic and reactive viscoelastic framework. [PDF]

Biomech Model Mechanobiol
Pellerito L, Avril S, Morici E, Sancataldo G, Zingales M.   +4 more
europepmc   +1 more source