Results 231 to 240 of about 92,115 (273)
Neoadjuvant chemotherapy or chemoradiotherapy for adenocarcinoma of the esophagus [PDF]
BackgroundThe optimal treatment strategy for patients with esophageal adenocarcinoma (EAC) remains undetermined. This study compared outcomes in patients undergoing neoadjuvant chemotherapy (nCT) and neoadjuvant chemoradiotherapy (nCRT) for EAC.MethodsPatients who underwent nCT or nCRT followed by surgery for EAC were identified from a prospective ...
Els Visser +11 more
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Rectal cancer: Neoadjuvant chemoradiotherapy
Best Practice & Research Clinical Gastroenterology, 2016The monolithic approach to apply the same schedule of preoperative 5-fluorouracil (5-FU)- or capecitabine-based chemoradiotherapy (CRT) to all patients with clinically staged TNM stage II/III rectal cancer need to be questioned. Five randomized trials have been completed to determine if the addition of oxaliplatin to preoperative 5-FU/capecitabine ...
Claus, Rödel +2 more
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Neoadjuvant chemoradiotherapy for resectable oesophageal cancer
Best Practice & Research Clinical Gastroenterology, 2018At present, treatment of potentially curable oesophageal cancer includes neoadjuvant chemoradiotherapy followed by oesophagectomy. Alternatively, neoadjuvant chemotherapy is used. To date, strong evidence on the superiority of one modality over the other has not been provided.
B.M. Eyck +8 more
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Neoadjuvant Chemoradiotherapy and Neoadjuvant Chemotherapy
2017Rectal cancer is a challenging disease to treat, and its optimal management requires a multidisciplinary approach with involvement of surgical, medical, and radiation oncologists.
Mohamed E. Salem, John L. Marshall
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Optimal indication of neoadjuvant chemoradiotherapy for pancreatic cancer
Langenbeck's Archives of Surgery, 2015Much attention has been paid to preoperative treatment as a new strategy especially for borderline resectable pancreatic cancer (BRPC). The purpose of this study was to define the optimal indication of neoadjuvant chemoradiotherapy (NACRT) for pancreatic cancer.We analyzed consecutive 184 patients who had undergone pancreatic resection in Nara Medical ...
Masayuki, Sho +11 more
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Neoadjuvant chemoradiotherapy for esophageal carcinoma: A meta-analysis
Surgery, 2005The effectiveness in improving survival of neoadjuvant chemoradiotherapy (NCRT) in patients undergoing surgery for esophageal carcinoma remains unclear.MEDLINE, the Cochrane Database of Systematic Reviews, BIOSIS Previews, and other resources were searched from January 1966 through January 2003.
Sarah E, Greer +3 more
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Anal Cancer: The End of the Road for Neoadjuvant Chemoradiotherapy?
Journal of Clinical Oncology, 2008The publication of the Radiation Therapy Oncology Group (RTOG) 98-11 Intergroup study in late April 2008, which randomly assigned patients to receive neoadjuvant fluorouracil (FU)/cisplatin followed by chemoradiotherapy (CRT) or to receive standard concomitant FU and mitomycin, provides an opportunity to examine the role of neoadjuvant chemotherapy ...
Rob, Glynne-Jones, Suzy, Mawdsley
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Future Oncology, 2019
Aim: To compare the clinical efficacy of neoadjuvant chemoradiotherapy (nCRT) and neoadjuvant chemotherapy (nCT) for esophageal cancer. Methods: Randomized controlled trials reporting on the comparison of nCRT and nCT for esophageal cancer were identified. Results: Three eligible randomized controlled trials were identified and included with a total of
Shao-Wu, Jing +7 more
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Aim: To compare the clinical efficacy of neoadjuvant chemoradiotherapy (nCRT) and neoadjuvant chemotherapy (nCT) for esophageal cancer. Methods: Randomized controlled trials reporting on the comparison of nCRT and nCT for esophageal cancer were identified. Results: Three eligible randomized controlled trials were identified and included with a total of
Shao-Wu, Jing +7 more
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Role of Chemoradiotherapy in Oesophageal Cancer — Adjuvant and Neoadjuvant Therapy
Clinical Oncology, 2014Despite low postoperative mortality rates, the long-term outcomes from surgical-based treatment for oesophageal cancer remain poor. Chemoradiotherapy (CRT), either given before surgical resection as neoadjuvant therapy or after resection as adjuvant therapy, has been postulated to improve these outcomes. This systematic review examines the evidence for
Gwynne, S. +3 more
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Neoadjuvant chemoradiotherapy of rectal carcinoma
Strahlentherapie und Onkologie, 2016The link between the blood count and a systemic inflammatory response (SIR) is indisputable and well described. Pretreatment hematological parameters may predict the overall clinical outcomes in many types of cancer. Thus, this study aims to systematically evaluate the relationship between baseline blood count levels and treatment response in rectal ...
Miroslav, Hodek +9 more
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