Results 41 to 50 of about 4,732,777 (361)

Neoadjuvant therapy alters the immune microenvironment in pancreatic cancer

Frontiers in Immunology, 2022
Pancreatic cancer has an exclusive inhibitory tumor microenvironment characterized by a dense mechanical barrier, profound infiltration of immunosuppressive cells, and a lack of penetration of effector T cells, which constitute an important cause for ...
Huiru Zhang, L. Ye, Xianjun Yu, K. Jin, Wei Wu   +4 more
semanticscholar   +1 more source

Preoperative Hormone Therapy in the Treatment of Breast Cancer: What Do We Know So Far?

Креативная хирургия и онкология, 2022
Breast cancer is the most common malignant disease in the world. One of the methods of treating breast cancer is neoadjuvant chemotherapy. Neoadjuvant chemotherapy (NCT) is now the standard of care for locally advanced breast cancer.
V. V. Vorotnikov, R. A. Pakhomova, A. V. Soinov, A. S. Gunina, I. V. Kopytich, M. G. Tsoi, S. A. Abdugafforov   +6 more
doaj   +1 more source

Neoadjuvant therapy for pancreatic cancer

Updates in Surgery, 2021
Multimodal treatment including surgery and chemotherapy is considered the gold standard treatment of pancreatic cancer by most guidelines. Neoadjuvant therapy (NAT) has been seen as a possible treatment option for resectable, borderline resectable and ...
J. Gugenheim, A. Crovetto, N. Petrucciani   +2 more
semanticscholar   +1 more source

Comparison of Standard Neoadjuvant Therapy and Total Neoadjuvant Therapy in Terms of Effectiveness in Patients Diagnosed with Locally Advanced Rectal Cancer

Medicina
Background/Objectives: The study aimed to compare the treatment effectiveness of patients with locally advanced rectal cancer undergoing standard neoadjuvant therapy or total neoadjuvant therapy.
Ayberk Bayramgil, Ahmet Bilici, Ali Murat Tatlı, Seda Kahraman, Yunus Emre Altintas, Fahri Akgul, Musa Barış Aykan, Jamshid Hamdard, Sema Sezgin Göksu, Mehmet Ali Nahit Şendur, Fatih Selçukbiricik, Ömer Fatih Ölmez   +11 more
doaj   +1 more source

Neoadjuvant therapy induces a potent immune response to sarcoma, dominated by myeloid and B cells.

Clinical Cancer Research, 2022
PURPOSE To characterize changes in the soft tissue sarcoma tumor immune microenvironment induced by standard neoadjuvant therapy with the goal of informing neoadjuvant immunotherapy trial design.
P. Goff, Laura Riolobos, B. LaFleur, M. Spraker, Y. D. Seo, K. Smythe, J. Campbell, R. Pierce, Yuzheng Zhang, Qianchuan He, Edward Y. Kim, S. Schaub, G. Kane, J. Mantilla, E. Chen, R. Ricciotti, Mathew J Thompson, L. Cranmer, M. Wagner, E. Loggers, Robin L. Jones, E. Murphy, W. Blumenschein, T. Mcclanahan, Jonathan K Earls, K. Flanagan, N. LaFranzo, Teresa S. Kim, S. Pollack   +28 more
semanticscholar   +1 more source

An open, observational clinical study of neoadjuvant therapy in resectable stage III non-small cell lung cancer

Frontiers in Oncology, 2023
BackgroundThis open, observational clinical study aimed to investigate the efficacy, safety and survival outcomes of neoadjuvant chemotherapy, neoadjuvant immunotherapy with(out) chemotherapy and neoadjuvant targeted therapy among resectable stage III ...
Yuwen Qi, Linping Gu, Jie Shen, Yaxian Yao, Yi Zhao, Shun Lu, Zhiwei Chen   +6 more
doaj   +1 more source

Treatment of Locally Advanced Rectal Cancer in the Era of Total Neoadjuvant Therapy

JAMA Network Open
Key Points Question Which neoadjuvant regimen is associated with the highest pathological complete response (pCR) in the treatment of locally advanced rectal cancer?
G. Turri, G. Ostuzzi, Giovanni Vita, Valeria Barresi, A. Scarpa, M. Milella, R. Mazzarotto, A. Ruzzenente, C. Barbui, C. Pedrazzani   +9 more
semanticscholar   +1 more source

Perioperative chemotherapy in colorectal cancer with peritoneal metastases: A global propensity score matched studyResearch in context

EClinicalMedicine, 2023
Summary: Background: There is a paucity of studies evaluating perioperative systemic chemotherapy in conjunction with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with colorectal cancer peritoneal ...
Peter H. Cashin, Jesus Esquivel, Stein G. Larsen, Winston Liauw, Nayef A. Alzahrani, David L. Morris, Vahan Kepenekian, Isabelle Sourrouille, Frédéric Dumont, Jean-Jacques Tuech, Cécilia Ceribelli, Beranger Doussot, Olivia Sgarbura, Francois Quenet, Olivier Glehen, Oliver M. Fisher   +15 more
doaj   +1 more source

Real-world analysis of leuprorelin acetate microspheres-based neoadjuvant therapy for patients with high-risk prostate cancer

Frontiers in Oncology
ObjectiveBoennuokang® leuprorelin acetate microspheres show a certain efficacy in patients with prostate cancer, but its utilization as neoadjuvant therapy in patients with high-risk prostate cancer remains unclear.
Changde Fu, Jun Xin, Jinjin Lai, Xu Zeng, Yongnan Wang, Wei Zhang   +5 more
doaj   +1 more source

Preoperative Management of Locally Advanced Rectal Cancer and the Role of Restaging MRI: An Australasian Perspective

World Journal of Colorectal Surgery, 2020
Background: Major advances in the management of locally advanced rectal cancer has led to controversies and varying clinical practices among colorectal surgeons, such as patient selection for neoadjuvant therapy and preferred regimen for neoadjuvant ...
Milton Mui, Joseph C. Kong, Glen R. Guerra, Alexander G. Heriot   +3 more
doaj   +1 more source