Cytoplasmic aggregation of TDP‐43 is a common pathological feature in amyotrophic lateral sclerosis, frontotemporal lobar degeneration, and Alzheimer's disease with TDP‐43 pathology. This study reports that wild‐type PDI slows down phase separation of TDP‐43 through direct interaction with TDP‐43.
Jia‐Qi Liu +14 more
wiley +1 more source
Utilizing Friction Energy on Nanoflowers (Zinc Oxide and Zinc Oxide/Neodymium Oxide) for Tribocatalysis of Doxycycline. [PDF]
Ivanova D +4 more
europepmc +1 more source
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang +11 more
wiley +1 more source
Advances in Dysprosium Recovery from Secondary Sources: A Review of Hydrometallurgical, Biohydrometallurgical and Solvometallurgical Approaches. [PDF]
Rudnik E.
europepmc +1 more source
In this study, chemoproteomics combined with genetic and functional analyses was integrated to identify SHMT2 as a covalent and functional target of gambogic acid (GA) in triple‐negative breast cancer (TNBC). Further validation demonstrated that GA selectively modifies the Cys241 site of SHMT2, triggering mitochondrial dysfunction, activating the Nrf2 ...
Tong Yang +15 more
wiley +1 more source
Pulsed dye versus neodymium-doped yttrium-aluminum-garnet lasers for refractory warts: a systematic review and meta-analysis. [PDF]
Kim JG.
europepmc +1 more source
PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao +7 more
wiley +1 more source
An Investigation of the Dissolution of Neodymium In Molten Neodymium Trichloride
openaire +1 more source
Early multimodal treatment of post-traumatic facial scarring: A case report. [PDF]
El Hajj H, Habre M.
europepmc +1 more source
Phase Diagrams and Piezoelectric Properties of Wurtzite Al1−x−yScxGdyN Heterostructural Alloys
This study demonstrates ferroelectricity and piezoelectric properties improvement of quaternary wurtzite Al1−x−yScxGdyN${\rm Al}_{1-x-y}{\rm Sc}_x{\rm Gd}_y{\rm N}$ films, guided by density functional theory calculations. Wurtzite Al1−x−yScxGdyN${\rm Al}_{1-x-y}{\rm Sc}_x{\rm Gd}_y{\rm N}$ films have a high optical bandgap, enhanced piezoelectric ...
Julia L. Martin +11 more
wiley +1 more source

