DDSurfer reconstructs cortical surfaces directly from diffusion MRI without requiring T1‐weighted scans. By fusing complementary microstructural features and learning diffeomorphic deformations, it efficiently generates accurate white matter and pial surfaces, improving geometric fidelity and morphometric reliability across datasets for robust surface ...
Chengjin Li +10 more
wiley +1 more source
Neonatal hyperbilirubinaemia: time for Italian recommendations? [PDF]
Borrelli AC +6 more
core +1 more source
Maternal smoking during pregnancy, other reproductive factors, and neonatal jaundice: A two-sample Mendelian randomization study. [PDF]
Geng W, Feng D, Qian J.
europepmc +1 more source
Structural Polymorphism of polyG Inclusions Revealed by In Situ Cryo‐Electron Tomography
Correlative cryo‐electron tomography in primary cortical neurons and NIID mouse brain tissue reveals that polyG inclusions are interconnected ribbon‐like assemblies rather than canonical amyloid fibrils. Multiple compartment‐specific ribbon states show distinct 26S proteasome accessibility, while cytoplasmic ribbons contact and deform ER‐like ...
Yunwen Qian +12 more
wiley +1 more source
This study reveals that NOTCH2NLC transcript variant 2 generates PolyGN2C‐iso2, an aggregating protein present within intranuclear inclusions of NIID patient tissues. A novel mouse model expressing PolyGN2C‐iso2 recapitulates white matter abnormalities and cognitive deficits, mechanistically linked to mitochondrial dysfunction. These findings support a
Kang Zhang +22 more
wiley +1 more source
Prevalence and Associated Risk Factors of Neonatal Sepsis in a Neonatal Intensive Care Unit of a Tertiary Hospital in Bangladesh: A Cross-Sectional Study. [PDF]
Akter F +4 more
europepmc +1 more source
Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies
This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang +7 more
wiley +1 more source
Enhancing perinatal care in Rwanda: building quality improvement into system strengthening. [PDF]
Tuyisenge L +10 more
europepmc +1 more source
Primary cultures of neuroblasts isolated from the nucleus basalis of Meynert of 12‐weeks‐old human foetuses were prepared. Whole‐cell patch‐clamp recordings were performed by injecting a depolarizing stimulus current (+500 pA; 500 ms), and the membrane voltage recorded; this stimulus current evoked periodic‐like oscillations in membrane voltage ...
Elisabetta Coppi +9 more
wiley +1 more source
Emerging Multidrug-Resistant Bacteria in Indonesian Neonatal Patients: Prevalence and Antimicrobial Resistance Profiles From Clinical Samples. [PDF]
Prastiyanto ME +6 more
europepmc +1 more source

