Results 101 to 110 of about 212,483 (315)

Neonatal sepsis

Journal of Pediatric and Neonatal Individualized Medicine, 2014
In this paper on neonatal sepsis, after a short presentation of etiopathogenesis and physiopathology, we will briefly present the clinical picture, the diagnosis and the therapy. Concerning diagnosis, we will focus our attention on procalcitonin (PCT),
Angelica Dessì, Chiara Pravettoni, Giovanni Ottonello, Francesca Birocchi, Francesca Cioglia, Vassilios Fanos   +5 more
doaj   +1 more source

A systematic scoping review of metrics utilized to measure antibiotic consumption in hospital settings

British Journal of Clinical Pharmacology, EarlyView.
Abstract Antimicrobial stewardship (AMS) programs were introduced to promote the judicious use of antimicrobials and to combat antimicrobial resistance. Quantifying antibiotic consumption is an important part of AMS initiatives to achieve these objectives.
Marjan Kandimahforoujaki, Kiplin A. Patanwala, Jan‐Willem C. Alffenaar, Asad E. Patanwala   +3 more
wiley   +1 more source

Parents' views on care of their very premature babies in neonatal intensive care units: a qualitative study [PDF]

, 2014
Background The admission of a very premature infant to the neonatal intensive care unit (NICU) is often a difficult time for parents. This paper explores parents’ views and experiences of the care for their very premature baby on NICU.
A Mitchell-DiCenso, A Sawyer, Alexandra Sawyer, AT Bhutta, C Kenner, CA Mundy, CG Roller, D Lupton, ER Van Teijlingen, G Gale, Gillian Gyte, Gillian Russell, GK Auslander, H Aagaard, H Harrison, H Wigert, Heike Rabe, I Hurst, J Fenwick, J Fenwick, J Sitzia, J Wereszczak, J Zeitlin, Jane Abbott, JL Jackson, JR Britton, KH Nykvist, L Arnold, L Cescutti-Butler, L Jones, Lelia Duley, LK Smith, M Redshaw, ME Redshaw, ME Redshaw, N Baum, P Aveyard, POPPY Steering Group, R Siegel, RJ Shaw, S Andaleeb, S Cockcroft, S Saigal, Susan Ayers, T Padden, TH Koh, V Braun, VC Smith, Y Chow, Y Freer   +49 more
core   +1 more source

Pentoxifylline dose finding trial in preterm neonates with suspected late onset sepsis (PTX‐trial)

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study (PTX‐trial) is to determine the optimal dose of pentoxifylline (PTX) in preterm neonates (gestational age < 30 weeks) with (suspected) late onset sepsis (LONS). Methods The PTX‐trial is a prospective multicentre open‐label sequential dose‐optimization study with an adapted continual reassessment method.
Serife Kurul, H. Rob Taal, Jan Mazela, Ryszard Lauterbach, Irwin K. M. Reiss, Karel Allegaert, Robert B. Flint, Sinno H. P. Simons   +7 more
wiley   +1 more source

Does bed rest for preeclampsia improve neonatal outcomes? [PDF]

, 2007
No. Strict bed rest in the hospital for pregnant women with preeclampsia does not appear to lower rates of perinatal mortality, neonatal mortality, or neonatal morbidity, including preterm birth, endotracheal intubations, or neonatal intensive care unit (
Cabrera, Maria Linda, Mackler, Leslie, McDiarmid, Todd   +2 more
core  

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Study protocol for a randomised cross-over trial of Neurally adjusted ventilatory Assist for Neonates with Congenital diaphragmatic hernias: the NAN-C study

Trials
Background Neurally adjusted ventilatory assist (NAVA) is a mode of mechanical ventilation that delivers oxygen pressures in proportion to electrical signals of the diaphragm.
Grace Poole, Christopher Harris, Sandeep Shetty, Theodore Dassios, Allan Jenkinson, Anne Greenough   +5 more
doaj   +1 more source

Facilitating the Parent/Child Bond: The Training, the Role, and the Perceived Self-Efficacy of Speech-Language Pathologists in the Neonatal Intensive Care Unit [PDF]

, 2012
The purpose of this study was to evaluate the facilitation of parent/child bonding through the roles, training, and perceived self-efficacy of speech-language pathologists working in the Neonatal Intensive Care Unit, as well as to investigate what ...
Taber, Shanley
core   +1 more source

Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children

British Journal of Clinical Pharmacology, EarlyView.
This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst, Pieter‐Jan Spiessens, Dorian Vanneste, Nada Dia, Matthias Gijsen, Isabel Spriet, Karel Allegaert, Erwin Dreesen, Anne Smits   +8 more
wiley   +1 more source

Therapeutic drug monitoring of antimicrobials in a paediatric setting: A retrospective single‐centre study

British Journal of Clinical Pharmacology, EarlyView.
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga, Stefano Agliardi, Riccardo Giossi, Alice Schianchi, Alessandra Romandini, Thomas Virdis, Silvia Nerini Molteni, Maria Luisa De Angelis, Stefania Paccagnini, Cecilia Gechtman, Alice Proto, Marco Fossati, Silvia Oliveri, Giulia Angela Pattarino, Elena Altieri, Agnese Graziosi, Arianna Pani, Romano Danesi, Stefano Martinelli, Costantino De Giacomo, Francesco Scaglione   +20 more
wiley   +1 more source