Results 161 to 170 of about 789,284 (243)

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Congenital Intraoral Synechiae: A Scoping Review of Airway, Feeding, and Surgical Management

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To map the existing literature on congenital intraoral synechiae and summarize reported anatomic patterns, clinical presentation, associated anomalies/syndromes, and outcomes to inform standardized diagnostic and therapeutic approaches. Data Sources PubMed, CINAHL, Embase, Web of Science, and Google Scholar were searched from January
Jason Bernier, Mathieu Bergeron
wiley   +1 more source

Clinic‐Based Transnasal Marsupialization for the Treatment of Congenital Dacryocystocele

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate the feasibility and outcomes of endoscopic intranasal marsupialization as treatment for congenital dacryocystocele, performed under topical anesthesia in a clinical setting. Study Design A retrospective review was conducted at a tertiary pediatric care hospital spanning from 2014 to 2024.
Camille Caron, Charlotte Lussier, Annie Lapointe, Rosanne Superstein, Erika Mercier   +4 more
wiley   +1 more source

Intrauterine Transfusions in Fetuses Affected by Parvovirus B19: Complications, Challenges and Outcomes

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This study evaluates the procedural characteristics, complications, and outcomes of intrauterine transfusion (IUT) for fetal anemia caused by parvovirus B19 infection during the 2023–2024 epidemic in Northwestern Europe. Method This multicenter observational study included all fetuses undergoing IUT for proven parvovirus B19‐induced ...
Banu Özbakir, Emma Van den Eede, Lone N. Nørgaard, Roland Devlieger, Karin Sundberg, Monique C. Haak, Femke Slaghekke   +6 more
wiley   +1 more source

Ileal duplication cyst linked to type 3A ileal atresia: a rare case report and review of the literature. [PDF]

Int J Surg Case Rep
Bilal HE, Alsir A, Yasin SA.
europepmc   +1 more source

Congenital Neonatal Intestinal Obstruction: Retrospective Analysis at Tertiary Care Hospital. [PDF]

J Neonatal Surg, 2016
Singh V, Pathak M.
europepmc   +1 more source

Role of Fetoscopic Airway Evaluation Immediately Preceding EXIT Procedure in Fetuses With Suspected Airway Obstruction

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This study describes the role of pre‐EXIT (Ex Utero Intrapartum Treatment) fetoscopic airway evaluation in fetuses with suspected airway obstruction. Methods Single center, retrospective, observational study including fetuses with suspected airway obstruction undergoing fetoscopic airway evaluation prior to EXIT between 2013 and 2025.
Daniel Sanin‐Ramirez, Joan Sabria, Josep M. Martinez, Mar Bennasar, Montserrat Izquierdo, Elisenda Eixarch, Eduard Gratacos   +6 more
wiley   +1 more source

Congenital Colonic Stenosis in a Preterm Infant: A Diagnostic Trap and the Potential Masking Effect of a Liquid Diet. [PDF]

Children (Basel)
Koh CC, Chang PF.
europepmc   +1 more source

Enterovirus infections in children

Pediatric Investigation, EarlyView.
Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Xiangpeng Chen, Lingyun Guo, Xiaobo Lei, Linqing Zhao, Mingyan Hei, Jun Shen, Ju Yin, Fei Li, Jikui Deng, Gang Liu, Yong Zhang, Zhengde Xie   +11 more
wiley   +1 more source