Results 131 to 140 of about 482,319 (343)

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Neonatal outcomes after fetal exposure to methadone and buprenorphine: national registry studies from the Czech Republic and Norway [PDF]

, 2018
Blanka Nechanská, Viktor Mravčík, Svetlana Skurtveit, Ingunn Olea Lund, Roman Gabrhelík, Anders Engeland, Marte Handal   +6 more
openalex   +1 more source

Early life growth patterns persist for 12 years and impact pulmonary outcomes in cystic fibrosis [PDF]

, 2018
BACKGROUND: In children with cystic fibrosis (CF), recovery from growth faltering within 2 years of diagnosis (Responders) is associated with better growth and less lung disease at age 6 years.
Farrell, Philip M., Lai, HuiChuan J., Sanders, Don B., Zhang, Zhumin   +3 more
core   +1 more source

Remimazolam Ameliorates Autistic‐Like Behaviors via Suppression of Ferroptosis in VTA Dopaminergic Neurons in a Mouse Model of ASD

Advanced Science, EarlyView.
The ultra‐short‐acting sedative remimazolam has a sustained therapeutic effect on the core symptoms of VPA‐exposed mice. Remimazolam, a GABA agonist, exerts its therapeutic effects by protecting dopamine neurons in the VTA of VPA‐exposed mice. Meanwhile, ferroptosis is the critical mechanism by which remimazolam protects VTA dopaminergic neurons and ...
Yuxin Zhang, Jianwei Lin, Chaoyang Tong, Xin Fu, Mengqin Shan, Yue Huang, Kan Zhang, Jijian Zheng   +7 more
wiley   +1 more source

Outcomes of Preterm Infants Admitted to Canadian NICUs Before and During the SARS-COV Pandemic

Children
Background: To better elucidate the impact of the SARS-COV pandemic on neonatal outcomes, we compared the health outcomes of infants born preterm requiring care in a Canadian NICU before and during the SARS-COV pandemic.
Marsha Campbell-Yeo, Amy Mireault, Fabiana Bacchini, Marc Beltempo, Prakesh S. Shah, Lynsey Alcock, Jeannette Comeau, Justine Dol, Amy Grant, Jonathan Gubbay, Brianna Hughes, Amos Hundert, Darlene Inglis, Yasmin Lalani, Morgan MacNeil, Thuy Mai Luu, Souvik Mitra, Michael Narvey, Karel O’Brien, Paula Robeson, Michelle Science, Canadian Neonatal Network (CNN) Investigators   +21 more
doaj   +1 more source

As Opioid Use Climbs, Neonatal Abstinence Syndrome Rises in New Hampshire [PDF]

, 2017
In this brief, author Kristin Smith analyzes inpatient hospital discharge data (2012–2015) to assess the prevalence of neonatal abstinence syndrome (NAS) in New Hampshire; describes one hospital’s successful program for treating pregnant women and ...
Smith, Kristin
core   +1 more source

Problematisation and regulation: bodies, risk, and recovery within the context of Neonatal Abstinence Syndrome [PDF]

, 2018
Background Neonatal Abstinence Syndrome (NAS) is an anticipated effect of maternal drug use during pregnancy. Yet it remains a contested area of policy and practice.
Chandler, Amy, Cooper, Sarah, Cunningham-Burley, Sarah, Elliott, Lawrie, Midgley, Paula, Whittaker, Anne   +5 more
core   +3 more sources

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Assessıng the predıctıve accuracy of blood-based bıomarkers ın neonatal outcomes for pregestatıonal dıabetes mellıtus [PDF]

Revista Brasileira de Ginecologia e Obstetrícia
Objective: This retrospective study aimed to investigate blood-based immune-inflammatory biomarkers (IIBs) in predicting neonatal outcomes in pregnancies with pregestational diabetes mellitus (PGDM).PIV[(neutrophil×platelet×monocyte)/lymphocyte)], SII ...
Ayse Cigdem Bayrak, Erdem Fadiloglu, Haticegul Tuncer, Edip Alptug Kir, Umutcan Kayikci, Ozgur Deren   +5 more
doaj   +1 more source

Association of traction force and adverse neonatal outcome in vacuum‐assisted vaginal delivery: A prospective cohort study [PDF]

, 2020
Kristina Pettersson, Magnus Westgren, Mats Blennow, Gunilla Ajne   +3 more
openalex   +1 more source