Results 201 to 210 of about 6,042,146 (340)

Piezo1 Upregulation in Monocyte‐Derived Macrophages Impairs Post‐Myocardial Infarction Cardiac Repair via Defective Efferocytosis and Enhanced Ferroptosis

open access: yesAdvanced Science, EarlyView.
This study reports early Piezo1 activation in bone marrow monocyte‐derived macrophages (MoMs) during myocardial infarction (MI), which governs the fate and function of recruited macrophages. The recruited MoMs with increased Piezo1 expression exhibit increased ferroptosis and defective efferocytosis, delayed clearance of dead cells and resolution of ...
Lu Peng   +19 more
wiley   +1 more source

Microglial Feimin Alleviates Cognitive Impairment in High‐Fat Diet‐Fed Mice

open access: yesAdvanced Science, EarlyView.
Microglial feimin deletion exacerbates lipotoxicity‐induced neuroinflammation and cognitive decline. In both in vitro and in vivo models, loss of feimin aggravated lipid droplet accumulation, IL‐1β/IL‐6 release, and neuronal injury through the PI3K–AKT–mTOR pathway, ultimately leading to severe neuronal apoptosis and cognitive impairment under high‐fat
Ran Gao   +12 more
wiley   +1 more source

Neonatal Outcomes of Extremely Preterm Infants From the NICHD Neonatal Research Network

open access: yesPediatrics, 2010
B. Stoll   +25 more
semanticscholar   +1 more source

Impact of COVID-19 on maternal and neonatal outcomes: a systematic review and meta-analysis

open access: yesClinical Microbiology and Infection, 2020
Francesca Di Toro   +11 more
semanticscholar   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

open access: yesAdvanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng   +9 more
wiley   +1 more source

Maternal, perinatal, neonatal, and postpartum outcomes following SARS-CoV-2 infection in pregnancy: A WHO multi-country prospective cohort study  [PDF]

open access: gold
WHO COVID-19 & Pregnancy Cohort Study Group   +38 more
openalex   +1 more source

3D Membrane Microstructures for Increased Efficiency in Blood‐Gas Transfer

open access: yesAdvanced Science, EarlyView.
Oxygenators for extracorporeal membrane oxygenation are based on hollow fiber membranes. They are associated with many complications, such as thrombosis or systemic inflammation during the therapy. By implementing 3D membrane microstructures for oxygenators, the transfer efficiency of oxygen and carbon dioxide is improved, which can lead to ...
Kai P. Barbian   +9 more
wiley   +1 more source

Ex Vivo Spatiotemporal Characterization of Spermatogenesis in Mouse Testicular Organoids

open access: yesAdvanced Science, EarlyView.
To date, in vitro spermatogenesis remains a challenge in reproductive medicine. In this study, Sun et al. developed a promising in vitro strategy to generate testicular organoids that enable germ cells from newborn mice to enter meiosis, complete chromosome recombination and synapsis, and develop into haploid spermatids.
Jiachen Sun   +9 more
wiley   +1 more source

The risk stratification of adverse neonatal outcomes in women with gestational diabetes (STRONG) study

open access: green, 2018
Basilio Pintaudi   +12 more
openalex   +2 more sources

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