Results 291 to 300 of about 482,319 (343)

The effect of intrapartum maternal fever on neonatal outcomes: a systematic review and meta-analysis. [PDF]

Front Pediatr
Ling Q, Wan H.
europepmc   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Associations of CRP and PCT levels with obstetric and neonatal outcomes: a prospective study. [PDF]

BMC Pregnancy Childbirth
Ates M, Calis P, Artiktay AG, Yilmaz C, Hirfanoglu IM, Erdem A, Erdem M.   +6 more
europepmc   +1 more source

Pentoxifylline dose finding trial in preterm neonates with suspected late onset sepsis (PTX‐trial)

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study (PTX‐trial) is to determine the optimal dose of pentoxifylline (PTX) in preterm neonates (gestational age < 30 weeks) with (suspected) late onset sepsis (LONS). Methods The PTX‐trial is a prospective multicentre open‐label sequential dose‐optimization study with an adapted continual reassessment method.
Serife Kurul, H. Rob Taal, Jan Mazela, Ryszard Lauterbach, Irwin K. M. Reiss, Karel Allegaert, Robert B. Flint, Sinno H. P. Simons   +7 more
wiley   +1 more source

Pregnancy, Delivery, and Neonatal Outcomes in Women with Tourette Syndrome or Chronic Tic Disorder. [PDF]

Mov Disord
Razaz N, Fernández de la Cruz L.
europepmc   +1 more source

Translation of a physiologically‐based pharmacokinetic model for dabigatran etexilate to the design of a safety and efficacy study in post‐partum women

British Journal of Clinical Pharmacology, EarlyView.
Aims To translate a PBPK model developed for the direct oral anticoagulant, dabigatran etexilate, the prodrug of dabigatran, based on data obtained from healthy men to healthy non‐pregnant, pregnant and post‐partum women. To evaluate safety and efficacy of dabigatran etexilate in post‐partum women using simulations and design a future clinical study to
Kayode Ogungbenro, Lorna Aucott, Farhad Kamali, Paul Ayuk   +3 more
wiley   +1 more source

Neonatal outcomes following previable rupture of membranes below 23 weeks' gestation. [PDF]

Eur J Pediatr
Grill A, Mikula F, Jansen S, Klein L, Rittenschober-Boehm J, Leitich H, Farr A, Berger A, Goeral K.   +8 more
europepmc   +1 more source

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

British Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić, Ivana Stević, Elvira Meni Maria Gkrinia, Dinko Vitezić, Slobodan Janković   +4 more
wiley   +1 more source

Effectiveness of nurses' training about mechanical ventilation weaning on neonatal outcomes. [PDF]

BMC Nurs
Alharbi MF, Marzouk SA, Alrashidi N, Abu-Alghayth MH, Mater EA, Ibrahim MA, Abdelmonem HH, Mohammed HA, Syan SA, Abdelrahem AS, Alshehri AD, Moursy SM, Almowafy AA, Ahmed FA.   +13 more
europepmc   +1 more source