Results 41 to 50 of about 482,319 (343)

The impact of gut microbiota on morbidities in preterm infants

Kaohsiung Journal of Medical Sciences
The gut microbiota undergoes substantial development from birth, and its development in the initial years of life has a potentially lifelong effect on the health of the individual.
Mei‐Yin Lai, Yin‐Hsi Chang, Chien‐Chung Lee, Neonatal Microbiome Outcomes Study Group (NEMO)   +3 more
doaj   +1 more source

EFFECT OF CONSANGUINEOUS MARRIAGES ON PEINATAL OUTCOME

Pakistan Armed Forces Medical Journal, 2020
Objective: To identify the characteristics of women in consanguineous marriage and their effects on reproductive behavior, adverse pregnancy and fetal outcomes. Study Design: Cross-sectional comparative study.
Abeera Choudry, Maria Habib, Zainab Shamem, Syeda Zubda Batool, Shafia Barkat, Mishal Naseem, Salma Nisar   +6 more
doaj  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Moderate hypothermia within 6 h of birth plus inhaled xenon versus moderate hypothermia alone after birth asphyxia (TOBY-Xe): a proof-of-concept, open-label, randomised controlled trial [PDF]

, 2015
Background Moderate cooling after birth asphyxia is associated with substantial reductions in death and disability, but additional therapies might provide further benefit.
Azzopardi, D, Bainbridge, A, Cady, E, Charles-Edwards, G, Deierl, A, Edwards, AD, Fagiolo, G, Franks, NP, Griffiths, J, Hajnal, J, Juszczak, E, Kapetanakis, B, Linsell, L, Maze, M, Omar, O, Robertson, NJ, Strohm, B, Tusor, N   +17 more
core   +2 more sources

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source

Comparative analysis of necrotizing enterocolitis in preterm infants born in Japan and born to mothers of Japanese ethnicity in California

Scientific Reports
Infants born in Japan are reported to have a low incidence of necrotizing enterocolitis (NEC) among countries, and these differences remained significant after adjusting for common clinical factors.
Satoshi Kusuda, Mihoko V. Bennett, Jeffrey B. Gould, Neonatal Research Network of Japan   +3 more
doaj   +1 more source

Evaluation of Pregnancy Outcomes in Pregnant Women with COVID-19 in Qazvin 1399

مجله اپیدمیولوژی ایران, 2021
Background and Objectives: The coronavirus disease 2019 (COVID-19) pandemic has raised concerns about high-risk groups in community. Due to physiologic changes in pregnancy, these women are prone to this infection; therefore, this study was conducted to ...
N Azh, H Pakniat, M Rajabi, F Ranjkesh
doaj  

The Comparison of Creatinine and Cystatin C Value in Preeclampsia Severity and Neonatal Outcome [PDF]

, 2016
Objectives: to compare the levels of creatinine and cystatin C with the severity of preeclampsia, and assess neonatal outcomes.Materials and Methods: Creatinine, cystatin C, and neonatal outcomes were assesed in 17 normotensive samples, 17 samples of ...
Wantania, J. (John), Winarto, A. (Abraham)   +1 more
core  

Maternal and neonatal outcomes by labor onset type and gestational age. [PDF]

, 2010
OBJECTIVE: We sought to determine maternal and neonatal outcomes by labor onset type and gestational age. STUDY DESIGN: We used electronic medical records data from 10 US institutions in the Consortium on Safe Labor on 115,528 deliveries from 2002 ...
Bailit, Jennifer L, Branch, D. Ware, Burkman, Ronald, Gonzalez-Quintero, Victor H, Gregory, Kimberly D, Haberman, Shoshana, Hatjis, Christos G, Hibbard, Judith U, Hoffman, Matthew K, Kominiarek, Michelle, Landy, Helain J, Landy, Howard, Learman, Lee A, Ramirez, Mildred M, Reddy, Uma M, Sun, Liping, Troendle, James, Van Veldhuisen, Paul, Wilkins, Isabelle, Zhang, Jun   +19 more
core   +1 more source