Results 161 to 170 of about 2,257,975 (340)
Advanced Science, EarlyView.This study investigates adenomyosis fibrosis in relation to nociceptive nerves. Nociceptive nerve‐secreted CGRP promotes RAMP1hi CD140b+ CD146+ fibroblast differentiation into myofibroblasts through ERK activation, causing severe fibrosis. Rimegepant‐induced CGRP/RAMP1 signaling blockade alleviates fibrosis and restores fertility in a mouse model. This
Zi Ye +11 more
wiley +1 more source
Advanced Science, EarlyView.Upon ischemia/reperfusion‐induced iron overload condition, neurons and astrocytes exhibit similar oxidative stress changes but opposite alterations in endogenous antioxidant defense mechanisms, leading to divergent ferroptotic outcomes. The iron deposition and neuronal loss are increased within the perilesional cortex of stroke patients ...
Yi Guo +17 more
wiley +1 more source
Advanced Science, EarlyView.A high resolution integrated cell atlas of the pig intestine provides insights into the genetic mechanisms of complex traits (Created in BioRender. Yu, P. (2025) https://BioRender.com/o14c563) Abstract The porcine intestinal tract is vital for nutrient absorption, immune regulation, and various physiological processes.
Pengfei Yu +14 more
wiley +1 more source
Cross-genetic determination of maternal and neonatal immune mediators during pregnancy. [PDF]
, 2018 BACKGROUND:The immune system plays a fundamental role in development during pregnancy and early life. Alterations in circulating maternal and neonatal immune mediators have been associated with pregnancy complications as well as susceptibility to ...
Ashwood, Paul +9 more
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Advanced Science, EarlyView.Humanized milk fat globules (MFG) mimic the native composition and structure of human milk, achieved through remodeling of milk fat globule membrane phospholipid composition and reconstruction of the tri‐layer membrane structure. These humanized MFG exhibit improved structural stability and digestibility, and enhance neurodevelopment in formula‐fed rat
Shaolei Wang +8 more
wiley +1 more source
Results of a regional cord blood screening programme for detecting neonatal hypothyroidism. [PDF]
, 1979 Paul G. Walfish +3 more
openalex +1 more source
Multiscale Construction, Evaluation, and Application of Organoids
Advanced Science, EarlyView.Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma +5 more
wiley +1 more source
Economic evaluation of cystic fibrosis screening: A Review of the literature, CHERE Working Paper 2006/6 [PDF]
Objectives: To critically examine the economic evidence on Cystic Fibrosis (CF) screening and to understand issues relating to the transferability of findings to the Australian context for policy decisions.
Jane Hall +4 more
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Audit in practice : surveillance for hypoglycaemia in the neonatal paediatric intensive care unit [PDF]
, 1998 Hypoglycaemia in neonates is defined as a blood glucose ≤ 2.6 mmol/1. Certain categories of babies are at particularly high risk of developing hypoglycaemia in the first few days of life, and are routinely monitored in the Neonatal Paediatric Intensive ...
Grech, Victor E., Soler, Paul
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