Results 201 to 210 of about 2,257,975 (340)

Identifying Key Questions and Challenges in Microchimerism Biology

open access: yesAdvanced Science, EarlyView.
This study identifies key unanswered questions about microchimerism, the presence of cells from one individual living in another. Experts highlight how these cells may affect health, pregnancy, and disease. This study outlines research priorities and challenges in detecting and studying these rare microchimeric cells, aiming to guide future discoveries
Kristine J. Chua   +31 more
wiley   +1 more source

Neonatal Screening for Cystic Fibrosis in Hungary-First-Year Experiences. [PDF]

open access: yesInt J Neonatal Screen, 2023
Xue A   +10 more
europepmc   +1 more source

The Pivotal Role of GR‐CAR Pathway in Fetal Programming of Hepatic Cytochrome P450 3A Alteration in Adulthood

open access: yesAdvanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) persistently upregulates hepatic CYP3A1/CYP2B1 in offspring via glucocorticoid receptor (GR) activation. In vivo and in vitro studies show GR promotes P300/CBP binding to the constitutive androstane receptor (CAR) promoter, sustaining histone acetylation (H3K9/K27ac) and enhancing CYP expression. The GR–CAR pathway
Xiaoxiang Sun   +9 more
wiley   +1 more source

Cord Blood-Based Neonatal Screening for Hemoglobinopathies in Northern Tunisia. [PDF]

open access: yesInt J Neonatal Screen
Ouragini H   +10 more
europepmc   +1 more source

Microglial Rack1 Deficiency Alleviates Alzheimer's Disease Pathology through Enhancing IGF1‐Mediated Astrocytic Phagocytosis

open access: yesAdvanced Science, EarlyView.
Alzheimer's disease (AD) is the most common neurodegenerative disorder. This study demonstrates that microglial Rack1 deficiency decreased Aβ deposition and neuroinflammation and ameliorated cognitive impairments in AD model mice by enhancing IGF1‐mediated astrocytic phagocytosis.
Jingdan Zhang   +13 more
wiley   +1 more source

Neonatal screening for primary and central congenital hypothyroidism: is it time to go Dutch? [PDF]

open access: yesEur Thyroid J, 2023
Boelen A   +3 more
europepmc   +1 more source

Benzene Derivatives from Ink Lead to False Positive Results in Neonatal Hyperphenylalaninemia Screening with Ninhydrin Fluorometric Method [PDF]

open access: gold, 2020
Shuren Feng   +10 more
openalex   +1 more source

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