ADAPT NXT: Fixed Cycles or Every‐Other‐Week IV Efgartigimod in Generalized Myasthenia Gravis
ABSTRACT Objective This phase 3b, open‐label, randomized ADAPT NXT study investigated the efficacy, safety, and tolerability of efgartigimod administered in either a fixed cycles dosing regimen (3 cycles of 4 once‐weekly infusions, with 4 weeks between cycles) or a cycle followed by every‐other‐week (Q2W) dosing.
Ali A. Habib+16 more
wiley +1 more source
Automated Detection of Congenital Heart Disease in Fetal Ultrasound Screening [PDF]
Prenatal screening with ultrasound can lower neonatal mortality significantly for selected cardiac abnormalities. However, the need for human expertise, coupled with the high volume of screening cases, limits the practically achievable detection rates.
arxiv
MedFMC: A Real-world Dataset and Benchmark For Foundation Model Adaptation in Medical Image Classification [PDF]
Foundation models, often pre-trained with large-scale data, have achieved paramount success in jump-starting various vision and language applications. Recent advances further enable adapting foundation models in downstream tasks efficiently using only a few training samples, e.g., in-context learning.
arxiv
Invasive Obstetric Procedures and Cesarean Sections in Women With Known Herpes Simplex Virus Status During Pregnancy. [PDF]
BackgroundNeonatal herpes is a potentially devastating infection that results from acquisition of herpes simplex virus (HSV) type 1 or 2 from the maternal genital tract at the time of vaginal delivery.
Drolette, Linda+7 more
core +1 more source
Myostatin Levels in SMA Following Disease‐Modifying Treatments: A Multi‐Center Study
ABSTRACT Objective This study investigated myostatin levels in SMA patients receiving disease‐modifying therapies (DMTs) to understand their relationship with treatment duration and functional status. Methods Our study includes both cross‐sectional and longitudinal analyses of myostatin levels in treated SMA patients.
Fiorella Piemonte+23 more
wiley +1 more source
NEONATAL SCREENING TO BE INTENSIFIED IN MALAYSIA – APRM-ISNS 2015 [PDF]
PENANG, 7 December 2015 The theme of the 9 Asia Pacific Regional Meeting for International Society for Neonatal Screening (APRMISNS) 2015, “New Insight in Neonatal Screening and The Way Forward” is both timely and appropriate, to bridge the knowledge
MPRC, Pusat Media & Perhubungan Awam
core
NICU Infants & SNHL: Experience of a western Sicily tertiary care centre [PDF]
Introduction: The variability of symptoms and signs caused by central nervous system (CNS) lesions make multiple sclerosis difficult to recognize,Introduction: This study adds the evaluation of the independent etiologic factors that may play a role in ...
Abita P+6 more
core +1 more source
Translating Muscle RNAseq Into the Clinic for the Diagnosis of Muscle Diseases
ABSTRACT Objective Approximately half of patients with hereditary myopathies remain without a definitive genetic diagnosis after DNA next‐generation sequencing (NGS). Here, we implemented transcriptome analysis of muscle biopsies as a complementary diagnostic tool for patients with muscle disease but no definitive genetic diagnosis after exome ...
Alba Segarra‐Casas+24 more
wiley +1 more source
Robust Neonatal Face Detection in Real-world Clinical Settings [PDF]
Current face detection algorithms are extremely generalized and can obtain decent accuracy when detecting the adult faces. These approaches are insufficient when handling outlier cases, for example when trying to detect the face of a neonate infant whose face composition and expressions are relatively different than that of the adult. It is furthermore
arxiv
Audit in practice : surveillance for hypoglycaemia in the neonatal paediatric intensive care unit [PDF]
Hypoglycaemia in neonates is defined as a blood glucose ≤ 2.6 mmol/1. Certain categories of babies are at particularly high risk of developing hypoglycaemia in the first few days of life, and are routinely monitored in the Neonatal Paediatric Intensive ...
Grech, Victor E., Soler, Paul
core