Results 101 to 110 of about 372,911 (292)

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

Advanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan, Jose Yeste, Mar Alvarez, Denise Marrero, Laura Casado‐Medina, Yvonne Richaud‐Patin, Olalla García‐Iglesias, Jagoda Litowczenko, Alba Morillas Garcia, Anton Guimerà, Xavi Illa, Rosa Villa, Angel Raya   +12 more
wiley   +1 more source

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Recurring Facial Erythema in an Infant

Case Reports in Pediatrics, 2016
Causes of facial rashes and erythema in infants are many but rarely only happen during feeding times which are commonly and sometimes wrongly attributed to food allergy.
Sam Hassan, Mary Jacqueline Saviour
doaj   +1 more source

Study of a Novel Bi‐Layered Thermoplastic Polyurethane Patch for Congenital Diaphragmatic Hernia

Advanced Materials Interfaces, EarlyView.
Large congenital diaphragmatic hernia remains a challenge due to the poor compatibility of current prostheses. To tackle this problem, a bilayer thermoplastic polyurethane patch with tunable mechanical properties is engineered, whose fibrous side supports rapid fibroblast and myoblast colonization, while the smooth film limits adhesions.
Guillaume Leks, Julie Favre, Manon Zislin, Rodolphe Migneret, Jordana Hirtzel, Vincent Ball, Cendrine Seguin, Anne Hebraud, Emeline Lobry, Guy Schlatter, Nadia Bahlouli, Hamdi Jmal, Benoît Frisch, Sylvie Fournel, Isabelle Talon   +14 more
wiley   +1 more source

The Role of Artificial Intelligence in Orthodontics for Determining Skeletal Age Based on Cervical Vertebra Maturation Degree: A Comprehensive Review

Health Science Reports
Background and Aims Dentofacial orthopedic treatment planning highly depends on the estimation of skeletal growth peak. In most cases, chronological age and biological age differ, some techniques estimate skeletal age by analyzing cervical vertebrae ...
Pegah Farzanegan, Mobina Zarabadi, Shaghayegh Najary, Mohammad Ali Tahmasbi, Mohammad Behnaz   +4 more
doaj   +1 more source

Efficacy of non-invasive high frequency oscillatory ventilation as post-extubation respiratory support in preterm neonates: a randomized controlled trial

Di-san junyi daxue xuebao, 2019
Objective To compare the efficacy of non-invasive high-frequency oscillatory ventilation (NHFOV) with nasal continuous positive airway pressure (NCPAP) in preterm infants aged 26+0~31+6 weeks as post-extubation respiratory support. Methods A total of 114
LI Huanhuan, LI Huanhuan, ZHU Xingwang, WANG Wanjun   +3 more
doaj   +1 more source

Access via the femoral vein [PDF]

, 2008
Central venous access via the femoral vein (FV) is safe, relatively easy and very usual in infants and children undergoing cardiac surgery for congenital heart disease. It has a low insertion-related complication rate.
Kruessell, Markus, Sreeram, Narayanswami, Trieschmann, U., Udink ten Cate, Floris   +3 more
core  

Advanced Design for Weakly Coupled Resonators by Automatic Active Optimization

Advanced Materials Technologies, EarlyView.
An Automatic Active Optimization (AAO) strategy integrates machine learning predictors and genetic algorithms in a closed‐loop workflow. By iteratively expanding its dataset with new discoveries, AAO overcomes the limits of conventional methods. This approach finds superior microstructural designs beyond the initial sample space. We demonstrate this on
Wei Yue, Yuan Gao, Fanping Sui, Jason Wang, Megan Teng, Peggy Tsao, Huicong Deng, Yande Peng, Liwei Lin   +8 more
wiley   +1 more source

Smart Closed‐Loop Systems in Personalized Healthcare: Advances and Outlook

Advanced Materials Technologies, EarlyView.
A smart closed‐loop e‐textile integrates multimodal sensing, onboard processing, wireless communication, and wearable power to enable real‐time physiological/biochemical monitoring and feedback‐controlled therapy. ABSTRACT Smart textiles represent a revolutionary frontier in healthcare, seamlessly blending fabric and advanced technologies to create ...
Safoora Khosravi, Sang Won Lee, Mohammad Abrar Uddin, Sina Hassanpoor, Neha Suvindran, Katherine Le, Harun Arkaz, Harishkumar Narayana, Saeid Soltanian, Danial Khorsandi, Negar Hosseinzadeh Kouchehbaghi, Taeil Kim, Yangzhi Zhu   +12 more
wiley   +1 more source

Non‐Invasive Multidimensional Capacitive Sensing for In Vivo Traumatic Brain Injury Monitoring

Advanced Materials Technologies, EarlyView.
Single‐electrode, multidimensional capacitive sensors noninvasively assess cerebral autoregulation and compliance for traumatic brain injury monitoring. ABSTRACT Traumatic brain injury (TBI) is a major cause of death and disability, but invasive intracranial pressure (ICP) monitoring is risky, and current non‐invasive methods lack the resolution and ...
Shawn Kim, Yu‐Jen Cheng, Tianyi Li, Nathan White, Xu Wang, Kristyn Ringgold, Lauren Neidig, Younghoon Kwon, Jae‐Hyun Chung   +8 more
wiley   +1 more source