Results 21 to 30 of about 66,012 (255)

Weaver Syndrome: A Rare Cause of Neonatal Macrosomia and Dysmorphism. A Case Report. [PDF]

Batna Journal of Medical Sciences
Weaver syndrome is a rare genetic disorder characterized by abnormally excessive growth both in utero and postnatally. It is associated with a mutation in the EZH2 gene, which leads to accelerated bone development and other clinical manifestations such
Fadila BENDAOUD, Hemza GUELLOUH
doaj   +1 more source

Development of Versatile Nanoparticle System for Efficient Drug Delivery into Pulmonary Endothelium

Advanced Science, EarlyView.
Pediatric acute respiratory distress syndrome (PARDS) suppresses the FOXF1 transcription factor and disrupts lung development. This study shows that the FOXF1‐activating small‐molecule compound, TanFe[F], can be precisely delivered to lung endothelial cells using the innovative LEDD nanoparticle system.
Afzaal N. Mohammed, Zicheng Deng, Arnab Misra, Marcus Orzabal, Ananya Kondapally, Enhong Li, Jonathan Do, Ying‐Wei Lan, Fatemeh Kohram, Hunter Blackburn, Andreas Damianos, Tanya V. Kalin, Vladimir V. Kalinichenko   +12 more
wiley   +1 more source

A critical moment for neonatology: appeals from the Lancet Child & Adolescent Health Commission

Italian Journal of Pediatrics
Background The Lancet Child and Adolescent Health Committee on the Future of Neonatology has published an important document on the future of neonatology to highlight the significant challenges hindering the development of research in this field of ...
Carlo Dani, Giovanni Corsello, Daniele De Luca, Massimo Agosti   +3 more
doaj   +1 more source

Neonatologists’ Resuscitation Decisions at Birth for Extremely Premature Infants. A Belgian Qualitative Study

Frontiers in Pediatrics, 2022
ObjectiveDeciding whether initiating or withholding resuscitation at birth for extremely preterm infants (EPIs) can be difficult due to uncertainty on outcomes. Clinical uncertainty generates ethical uncertainty.
Alice Cavolo, Bernadette Dierckx de Casterlé, Gunnar Naulaers, Chris Gastmans   +3 more
doaj   +1 more source

Setting up mother–infant pair lactation studies with biobanking for research according to regulatory requirements

British Journal of Clinical Pharmacology, EarlyView.
Within the ConcePTION project we set out to design two mother–infant pair studies collecting breast milk and plasma from the mother and plasma from the infant (for metformin and prednisolone) in order to demonstrate the premises and conditions for investigating potential drug transfer in association with breastfeeding.
Mats Hansson, Ida Björkgren, Jenny Svedenkrans, Helena Backman, Jarl Hellman, Linda Englund‐Ögge, Mikaela Magnusson, Inger Lindström, Andrea Wutte, Erica Sundell, Pawel Baranczewski, Laura Shaughnessy   +11 more
wiley   +1 more source

Effects of Early Myocardial Postnatal Maturation on Tolerance to Atrial Tachycardia With Altered Loading Conditions: An in vivo Swine Model

Frontiers in Pediatrics, 2020
Post-natal maturation of the myocardium starts shortly after birth and could affect how clinicians should provide hemodynamic support during this transition.
Etienne Fortin-Pellerin, Nee S. Khoo, Nee S. Khoo, James Y. Coe, Lindsay Mills, Po-Yin Cheung, Lisa K. Hornberger, Lisa K. Hornberger   +7 more
doaj   +1 more source

Selected Abstracts of the 18th International Workshop on Neonatology and Pediatrics; Cagliari (Italy); October 19-22, 2022

Journal of Pediatric and Neonatal Individualized Medicine, 2022
Selected Abstracts of the 18th International Workshop on Neonatology and Pediatrics; Cagliari (Italy); October 19th-22nd, 2022   The Workshop has been organized with the patronage of UENPS (Union of European Neonatal and Perinatal Societies), UMEMPS ...
--- Various Authors
doaj   +1 more source

Metabolomics Applied in Neonatology

Bioanalysis, 2014
Over the past two decades, host-response biomarkers have been extensively used by clinicians for a better understanding of normal biological processes, the complexity and severity of illnesses, or pharmacological responses to therapeutic intervention. A myriad of information can be drawn from the gender, age, dietary intake and the disease history of ...
Iacovidou, N, Syggelou, A, Chalkias, A, ATZORI, LUIGI, Xanthos, T, FANOS, VASSILIOS   +5 more
openaire   +4 more sources

Pentoxifylline dose finding trial in preterm neonates with suspected late onset sepsis (PTX‐trial)

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study (PTX‐trial) is to determine the optimal dose of pentoxifylline (PTX) in preterm neonates (gestational age < 30 weeks) with (suspected) late onset sepsis (LONS). Methods The PTX‐trial is a prospective multicentre open‐label sequential dose‐optimization study with an adapted continual reassessment method.
Serife Kurul, H. Rob Taal, Jan Mazela, Ryszard Lauterbach, Irwin K. M. Reiss, Karel Allegaert, Robert B. Flint, Sinno H. P. Simons   +7 more
wiley   +1 more source

Acute toxicity of ADB‐CHMINACA ‐ a case series of patients with pronounced central nervous symptoms including the posterior reversible encephalopathic syndrome

British Journal of Clinical Pharmacology, EarlyView.
Aim This report presents a series of 16 patients who were admitted to the emergency department following confirmed intake of the potent synthetic cannabinoid ADB‐CHMINACA. Methods The cases are drawn from a prospective observational study following the recreational use of synthetic cannabinoids.
Maren Hermanns‐Clausen, Michaela Sommer, Annette Zschiesche, Verena Angerer, Martin Scheu, Florian Eyer, Johannes Nadler, Volker Auwärter   +7 more
wiley   +1 more source