Results 161 to 170 of about 68,698 (287)

Differential segment‐specific signalling pathways for guanylate cyclase C‐activated anion secretion in murine ileocolon

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Guanylate cyclase‐C (GC‐C) is the receptor for endogenous (uro)guanylin peptides, bacterial toxins and pharmacological analogues. Receptor activation leads to intestinal fluid loss, but also activates an antiproliferative pathway and is a promising target in colorectal cancer therapy.
Renjie Xiu, Johannes Reiner, Franz Hofmann, Azam Salari, Ursula Seidler   +4 more
wiley   +1 more source

Spectroscopic Microvascular Blood Detection From the Endoscopically Normal Colonic Mucosa: Biomarker for Neoplasia Risk [PDF]

, 2008
Hemant K. Roy, Andrew Gomes, Vladimir Turzhitsky, Michael J. Goldberg, Jeremy D. Rogers, Sarah Ruderman, Kim Lea Young, Alex Kromine, Randall E. Brand, Mohammed Jameel, Parmede Vakil, Nahla Hasabou, Vadim Backman   +12 more
openalex   +1 more source

Regulation of R‐Loop Dynamics by Proteins and Long Noncoding RNAs: An Emerging Paradigm for Cancer Treatment

Cancer Science, EarlyView.
R‐loops are three‐stranded nucleic acid structures whose dysregulation leads to genomic instability and cancer progression. This review summarizes the protein and lncRNA machineries that regulate R‐loop dynamics and discusses the therapeutic potential of targeting these pathways in cancer.
Miho M. Suzuki, Keiko Shinjo, Tatsunori Nishimura, Yutaka Kondo   +3 more
wiley   +1 more source

Hospitalization burden associated with malignant neoplasia and in situ carcinoma in vulva and vagina during a 5-year period (2009–2013) in Spain: An epidemiological study

, 2018
Noelia López, Ángel Gil de Miguel, Raquel Pascual-García, José Manuel Ramón y Cajal, Ruth Gil-Prieto   +4 more
openalex   +1 more source

Single‐Cell and Multiomic Analysis Reveals Neutrophil Heterogeneity and Prognostic Value in Cervical Lesions

Cancer Science, EarlyView.
This study is the first to identify a novel neutrophil subpopulation, N4, that is closely associated with the progression of cervical cancer. Characterized by high PLAU expression and specific interactions with tumor cells, N4 neutrophils were shown to promote tumor growth and immune modulation.
Ze Wang, Liang Zhuang, Shiyi Liu, Canhui Cao, Shimin Chen, Nan Yu, Xiaoyuan Huang, Tao Zhang   +7 more
wiley   +1 more source

Underestimation of the horizontal extent of ulcerative colitis-associated neoplasia may lead to incomplete endoscopic resection and subsequent recurrence. [PDF]

Therap Adv Gastroenterol
Murakami S, Sugimoto S, Iwao Y, Takabayashi K, Kiyohara H, Yoshimatsu Y, Sakakibara R, Kaieda Y, Shigehara A, Hosoe N, Kato M, Mikami Y, Kanai T.   +12 more
europepmc   +1 more source

Knowledge and application of sonographic scoring models for ovarian cancer management among gynecologists in Saudi Arabia: a cross-sectional study. [PDF]

PeerJ
Aldahlawi R.
europepmc   +1 more source

S1‐Guideline for diagnosis and therapy of necrobiosis lipoidica

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Necrobiosis lipoidica (NL) is a rare granulomatous skin disease of unknown etiology that occurs frequently in association with diabetes mellitus and other comorbidities. The predilection site is the lower leg, particularly the pretibial areas. The exact pathogenesis remains unclear.
Cornelia Erfurt‐Berge, Regina Renner, Melanie Peckruhn, Jörg Tittelbach, Dorothea Terhorst‐Molawi, Friederike Kauer, Joachim Dissemond   +6 more
wiley   +1 more source

Is endoscopic radiofrequency ablation safe and effective for treating rare neuroendocrine tumors of the minor papilla? [PDF]

Endoscopy
Wang R, Su Z, Zhang H, Zhang J, Yue P, Meng W, Li X.   +6 more
europepmc   +1 more source

Colposcopy in diagnosis and treatment of cervical intraepithelial neoplasia (CIN)

, 1987
Wouter Huisman, Hans Wijnen
openalex   +1 more source